220091-43-0

Basic information

• Product Name: (3-methyl-crotonoyl)-(4-nitro-benzenesulfonyl)-amine
• Synonyms: (3-methyl-crotonoyl)-(4-nitro-benzenesulfonyl)-amine
• CAS NO: 220091-43-0
• Molecular Weight: 284.293
• Mol File: 220091-43-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3-methyl-crotonoyl)-(4-nitro-benzenesulfonyl)-amine(CAS DataBase Reference)
• NIST Chemistry Reference: (3-methyl-crotonoyl)-(4-nitro-benzenesulfonyl)-amine(220091-43-0)
• EPA Substance Registry System: (3-methyl-crotonoyl)-(4-nitro-benzenesulfonyl)-amine(220091-43-0)

Safety Data

• Hazardous Substances Data: 220091-43-0(Hazardous Substances Data)

Upstream product

• 541-47-9 3-Methylbutenoic acid 
• 3350-78-5 3,3-Dimethylacryloyl chloride 
• 98-74-8 4-Nitrobenzenesulfonyl chloride 
• 6325-93-5 p-nitrobenzenesulfonamide 

Relevant articles and documents

4-endo-trig cyclization processes using bis(collidine)bromine(i) hexafluorophosphate as reagent: Preparation of 2-oxetanones, 2-azetidinones, and oxetanes

Reaction in methylene chloride of bis(collidine)bromine(I) hexafluorophosphate with α,β-unsaturated acids and α,β-unsaturated N- sulfonamides was found to lead diastereospecifically to the corresponding 2- oxetanones and 2-azetidinones in moderate yields (23-60%), by an almost unknown 4-endo cyclization. This process allow the synthesis of these interesting classes of products in one step from common substrates. Similarly, the reaction of cinnamic alcohols led, by the same cyclization procedure, to oxetanes (20-36%); the presence of a gem-dimethyl group in α of the alcohol function appeared beneficial.