220498-07-7

Basic information

• Product Name: (R)-2-CYCLOHEXYL SUCCINIC ACID-1-METHYL ESTER
• Synonyms: (R)-2-CYCLOHEXYL SUCCINIC ACID-1-METHYL ESTER;(R)-3-CYCLOHEXYL-3-(METHOXYCARBONYL)PROPIONIC ACID;(R)-2-Cyclohexylsuccinicacid1-methylester(e.e.);(R)-2-CYCLOHEXYLSUCCINIC ACID-1-METHYL ESTER 95%, (98% E.E.);(R)-2-Cyclohexyl succinic acid-1-methyl ester, 98% ee;(R)-4-Methoxy-3-cylcohexyl-4-oxobutanoicAcid
• CAS NO: 220498-07-7
• Molecular Formula: C11H18O4
• Molecular Weight: 214.26
• Mol File: 220498-07-7.mol
• Article Data: 4

Chemical Properties

• Melting Point: 46.1 °C
• Boiling Point: 314.39°C (rough estimate)
• Flash Point: 130.7 °C
• Appearance: pale yellow needle-like crystals
• Density: 1.1328 (rough estimate)
• Vapor Pressure: 1.01E-05mmHg at 25°C
• Refractive Index: 1.6000 (estimate)
• Storage Temp.: Refrigerator (+4°C)
• CAS DataBase Reference: (R)-2-CYCLOHEXYL SUCCINIC ACID-1-METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-CYCLOHEXYL SUCCINIC ACID-1-METHYL ESTER(220498-07-7)
• EPA Substance Registry System: (R)-2-CYCLOHEXYL SUCCINIC ACID-1-METHYL ESTER(220498-07-7)

Safety Data

• Safety Statements: 24/25-22
• Hazardous Substances Data: 220498-07-7(Hazardous Substances Data)

Usage

Chemical Properties

pale yellow needle-like crystals

InChI:InChI=1/C11H18O4/c1-15-11(14)9(7-10(12)13)8-5-3-2-4-6-8/h8-9H,2-7H2,1H3,(H,12,13)/p-1/t9-/m1/s1

Upstream product

• 21985-20-6 3-cyclohexylidene-4-methoxy-4-oxobutanoic acid 
• 246854-60-4 tert-butylamine salt of 2-cyclohexylidenesuccinic acid 1-methyl ester 
• 40745-21-9 dimethyl 2-cyclohexylidenesuccinate 

Relevant articles and documents

Conjugate addition of nitroalkanes to dimethyl maleate. Regioselective formation of both monoesters of 2-alkylsuccinic acids

Diesters of (E)-2-alkylidenesuccinic acids obtained by conjugate addition of nitroalkanes to dimethyl maleate can be selectively monohydrolyzed at the more reactive carboxyl group to the corresponding half-ester. Alternatively, total hydrolysis to the dia

Homogeneous asymmetric hydrogenation using phosphine ligands of transition metals

A process for the preparation of an enantiomerically enriched 2-substituted succinic acid derivative of formula 2, which comprises asymmetric hydrogenation of the dehydro precursor of formula 7 or 8, or a mixture thereof wherein R1and R2/