22083-78-9 Usage
Description
2-PYRROLIDIN-2-YLPYRIDINE, also known as (S)-2-(2-Pyrrolidinyl)-pyridine, is an organic compound with a unique molecular structure that features a pyridine ring fused to a pyrrolidine ring. 2-PYRROLIDIN-2-YLPYRIDINE is known for its catalytic properties and is widely utilized in various chemical reactions, particularly in the field of organic synthesis.
Uses
Used in Chemical Synthesis:
2-PYRROLIDIN-2-YLPYRIDINE is used as a catalyst for the enantioselective addition of diethylzinc to aldehydes. This reaction is crucial in the formation of optically active secondary alcohols, which are essential building blocks in the synthesis of various pharmaceuticals, agrochemicals, and natural products. The application of 2-PYRROLIDIN-2-YLPYRIDINE as a catalyst in this process enables the production of these valuable compounds in high yields with excellent enantioselectivity.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-PYRROLIDIN-2-YLPYRIDINE is used as a key intermediate in the synthesis of various drug candidates. Its unique structure and reactivity make it an attractive starting material for the development of novel therapeutic agents with potential applications in the treatment of various diseases and medical conditions.
Used in Research and Development:
2-PYRROLIDIN-2-YLPYRIDINE is also employed as a valuable research tool in academic and industrial laboratories. Its use as a catalyst in enantioselective reactions allows chemists to explore new synthetic routes and develop innovative methodologies for the preparation of complex organic molecules. 2-PYRROLIDIN-2-YLPYRIDINE's versatility and utility in catalysis make it an indispensable asset in the field of chemical research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 22083-78-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,0,8 and 3 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 22083-78:
(7*2)+(6*2)+(5*0)+(4*8)+(3*3)+(2*7)+(1*8)=89
89 % 10 = 9
So 22083-78-9 is a valid CAS Registry Number.
22083-78-9Relevant articles and documents
Metal complexes of chiral pyridine ligands. X-ray structure of nitratobispyridine>copper(II) nitrate
Bacchi, Alessia,Chelucci, Giorgio,Grandino, Manlio,Minardi, Giovannina,Pelizzi, Corrado,et al.
, p. 659 - 664 (1994)
Cobalt(II), nickel(II), and copper(II) complexes of 2-pyridine (L) have been synthesized and characterized.The crystal structure of the complex NO3 has been determined by X-ray diffraction.Crystals are monoclinic, space group P2+, with a = 10.766(3), b = 7.525(2), c = 13.447(4) Angstroem, β = 104.64(2) deg, and Z = 2.The structure consists of + cations and NO3- anions.The copper atom has a distorted trigonal bipyramidal coordination geometry with the two pyrrolidine nitrogens and one nitrate oxygen occupying the equatorial positions and the two pyridine nitrogens at the apices.The crystalline cohesion is ensured by a network of hydrogen bonds involving the pyrrolidine groups as donors and both coordinate and uncoordinate nitrates as acceptors.KEY WORDS: Metal complexes, chiral, pyridine, ligands, pyridine derivatives.
HETEROARYL COMPOUNDS AS CXCR4 INHIBITORS, COMPOSITION AND METHOD USING THE SAME
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, (2019/04/16)
The present disclosure provides heteroaryl compounds of Formula (I), processes for their preparation, pharmaceutical compositions containing them, and their use in the treatment of diseases and disorders, arising from or related to the CXCR4 pathway.
