220928-01-8 Usage
General Description
(R)-3-AMINOPIPERIDIN-2-ONE, also known as R-(+)-3-amino-2-piperidone, is a chemical compound with the molecular formula C5H10N2O. It is an amino acid derivative that has been studied for its potential applications in the pharmaceutical industry. (R)-3-AMINOPIPERIDIN-2-ONE has been investigated for its role as a building block in the synthesis of various pharmaceutical agents and bioactive compounds. It is also used as a chiral auxiliary for the asymmetric synthesis of complex organic molecules. Additionally, (R)-3-aminopiperidin-2-one has shown potential as a precursor in the production of numerous pharmaceuticals and agrochemicals due to its unique chemical properties and versatile reactivity. Overall, this compound has garnered attention for its potential utility in drug discovery and development processes.
Check Digit Verification of cas no
The CAS Registry Mumber 220928-01-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,0,9,2 and 8 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 220928-01:
(8*2)+(7*2)+(6*0)+(5*9)+(4*2)+(3*8)+(2*0)+(1*1)=108
108 % 10 = 8
So 220928-01-8 is a valid CAS Registry Number.
220928-01-8Relevant articles and documents
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Lyle,Spicer
, p. 1133 (1970)
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Photochemical rearrangement of N -chlorolactams: A route to N -heterocycles through concerted ring contraction
Winter, Dana K.,Drouin, Alexandre,Lessard, Jean,Spino, Claude
supporting information; experimental part, p. 2610 - 2618 (2010/06/17)
We report a novel ring contraction allowing the direct conversion of N-chlorolactams to their corresponding ring-contraction N-heterocycles upon photolysis. Results show that the rearrangement occurs with a variety of N-chlorolactams and that the greater the substitution at the migrating carbon, the greater the yield of product. Importantly, stereochemistry at the migrating carbon is conserved in the product. Rearranged products were isolated as their methyl carbamates in yields varying from 17% to 58%, with the major side product being the recyclable parent lactam.
Chemoenzymatic enantioselective synthesis of 3-hydroxy-2-pyrrolidinones and 3-hydroxy-2-piperidinones
Kamal, Ahmed,Ramana, K. Venkata,Ramana, A. Venkata,Babu, A. Hari
, p. 2587 - 2594 (2007/10/03)
The enantioselective synthesis of 3-hydroxypyrrolidin-2-ones and 3-hydroxy piperidin-2-ones has been carried out in high enantiomeric excess employing immobilized lipase from Pseudomonas cepacia.
