221101-61-7

Basic information

• Product Name: AMINO-BIPHENYL-4-YL-ACETIC ACID
• Synonyms: AMINO-BIPHENYL-4-YL-ACETIC ACID;AMINO([1,1'-BIPHENYL]-4-YL)ACETIC ACID;a-AMino-biphenyl-4-acetic acid;2-Amino-2-(4-biphenylyl)acetic acid;2-Amino-2-(4-phenylphenyl)acetic acid
• CAS NO: 221101-61-7
• Molecular Formula: C₁₄H₁₃NO₂
• Molecular Weight: 227.26
• Product Categories: pharmacetical
• Mol File: 221101-61-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 414.5 °C at 760 mmHg
• Flash Point: 204.5 °C
• Appearance: /
• Density: 1.217 g/cm³
• Vapor Pressure: 1.3E-07mmHg at 25°C
• Refractive Index: 1.619
• PKA: 1.93±0.10(Predicted)
• CAS DataBase Reference: AMINO-BIPHENYL-4-YL-ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: AMINO-BIPHENYL-4-YL-ACETIC ACID(221101-61-7)
• EPA Substance Registry System: AMINO-BIPHENYL-4-YL-ACETIC ACID(221101-61-7)

Safety Data

• Hazardous Substances Data: 221101-61-7(Hazardous Substances Data)

Usage

General Description

Amino-biphenyl-4-yl-acetic acid is a chemical compound that has found potential applications in pharmaceutical industry. Its molecular formula is usually represented as C14H13NO2. The key structural feature of this compound is the presence of an amino group linked with a biphenyl group, paired with an acetic acid moiety. The physical and chemical properties of this compound could vary based on the specific positions of these groups on the molecular structure. It is anticipated to have various biological activities that could make it a useful candidate in the synthesis of drugs and biologically active molecules. The safety, toxicity, and potential health effects of this chemical are aspects that would require further detailed studies.

InChI:InChI=1/C14H13NO2/c15-13(14(16)17)12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9,13H,15H2,(H,16,17)/t13-/m1/s1

Upstream product

• 2350-89-2 p-vinylbiphenyl 
• 5449-21-8 2-([1,1’-biphenyl]-4-yl)-2-oxoacetic acid 
• 369403-44-1 2-([1,1'-biphenyl]-4-yl)-2-((tert-butoxycarbonyl)amino)acetic acid 

Relevant articles and documents

Synthesis method of 2-([1, 1 '-biphenyl]-4-yl)-2-glycine compound

The invention relates to a synthesis method of a 2-([1, 1 '-biphenyl]-4-yl)-2-glycine compound. The method comprises the following steps: performing suzuki reaction on a compound as shown in a formulaI and a compound as shown in a formula II in the presence of alkali, a solvent and a catalyst under inert gas protection and microwave-assisted conditions to prepare an intermediate compound, and then deprotecting the intermediate compound to prepare a compound as shown in a formula III, wherein the structural formula of the compound shown in the formula I is shown in the specification, the structural formula of the compound shown in the formula II is shown in the specification, the structural formula of the compound shown in the formula III is shown in the specification, and in the formula Iand the formula III, R is one of H, alkyl, alkoxy, halogen and trifluoromethyl. The synthesis method is low in toxicity, high in safety coefficient, easy and convenient to operate, easy to control and efficient in reaction, and the yield reaches up to 81% or above. In the synthesis method, microwave assistance is added for a certain time in the suzuki reaction process, so that the reaction is promoted, the reaction efficiency is effectively improved, and the reaction time is shortened.