22112-77-2

Basic information

• Product Name: meso-Tetra (4-chlorophenyl) porphine
• Synonyms: meso-Tetra (4-chlorophenyl) porphine;21H,23H-Porphine, 5,10,15,20-tetrakis(4-chlorophenyl)-;5,10,15,20-tetrakis(4-chlorophenyl)-21,22-dihydroporphyrin;5,10,15,20-tetrakis(para-chlorophenyl)porphyrin;H2t(4-Cl)pp;meso-tetrakis-(4-chlorophenyl)porphyrin;tetra(para-chlorophenyl)porphyrin;TPP(4-Cl)4
• CAS NO: 22112-77-2
• Molecular Formula: C₄₄H₂₆Cl₄N₄
• Molecular Weight: 752.51604
• Mol File: 22112-77-2.mol
• Article Data: 64

Chemical Properties

• Melting Point: >27 °C
• Appearance: /
• Density: 1.398g/cm³
• Refractive Index: 1.702
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: meso-Tetra (4-chlorophenyl) porphine(CAS DataBase Reference)
• NIST Chemistry Reference: meso-Tetra (4-chlorophenyl) porphine(22112-77-2)
• EPA Substance Registry System: meso-Tetra (4-chlorophenyl) porphine(22112-77-2)

Safety Data

• Hazardous Substances Data: 22112-77-2(Hazardous Substances Data)

Usage

General Description

Meso-tetra(4-chlorophenyl)porphine is a chemical compound that belongs to the group of porphyrins, which are heterocyclic macrocycles containing four pyrrole rings. meso-Tetra (4-chlorophenyl) porphine is a type of porphyrin that contains four 4-chlorophenyl groups attached to the pyrrole rings. It has been studied for its potential applications in photodynamic therapy, a treatment that uses light-sensitive compounds to selectively destroy cancer cells. Meso-tetra(4-chlorophenyl)porphine has also been investigated for its use in chemical sensors, catalysis, and as a model system for studying the properties of natural porphyrin compounds. Furthermore, it has been utilized in the synthesis of other porphyrin derivatives for various research and industrial purposes.

InChI:InChI=1/C44H26Cl4N4/c45-29-9-1-25(2-10-29)41-33-17-19-35(49-33)42(26-3-11-30(46)12-4-26)37-21-23-39(51-37)44(28-7-15-32(48)16-8-28)40-24-22-38(52-40)43(36-20-18-34(41)50-36)27-5-13-31(47)14-6-27/h1-24,49,52H/b41-33-,41-34-,42-35-,42-37-,43-36-,43-38-,44-39-,44-40-

Upstream product

• 109-97-7 pyrrole 
• 104-88-1 4-chlorobenzaldehyde 
• 137018-26-9 2,2'-((4-chlorophenyl)methylene)bis(1H-pyrrole) 
• 13169-71-6 2-(4-chlorobenzoyl)pyrrole 
• 99-91-2 para-chloroacetophenone 
• 7099-88-9 4-chlorophenylglyoxylic acid 
• 275-51-4 azulene 
• 248606-50-0 5,10,15,20-tetrakis(4-chlorophenyl)porphyrinogen 
• 121-33-5 vanillin 
• 154047-16-2 (4-Chloro-phenyl)-(1H-pyrrol-2-yl)-methanol 
• 22112-84-1 tetrakis(4-aminophenyl)porphyrin 

Downstream Products

• 36965-70-5 5,10,15,20-tetrakis(p-chlorophenyl)porphyrin iron(III) chloride 
• 134960-79-5 Pd(5,10,15,20-tetra(4-chlorophenyl)porphyrin-2H) 
• 57774-14-8 Ni(2+)-α,β,γ,δ-tetra(4-chlorophenyl)porphine 
• 75964-88-4 Ag(p-ClTPP) 
• 771474-29-4 C₄₄H₂₄AuCl₄N₄⁽¹⁺⁾ 
• 1208169-34-9 [Mn(TClPP)(H₂O)2]ClO₄ 
• 55915-17-8 5,10,15,20-tetrakis(p-chlorophenyl)porphyrin cobalt (II) 
• 29116-33-4 5,10,15,20-tetrakis(4-chlorophenyl)porphyrinatozinc(II) 

Relevant articles and documents

Insights into the new cadmium(II) metalloporphyrin: Synthesis, X-ray crystal structure, Hirshfeld surface analysis, photophysical and cyclic voltammetry characterization of the (morpholine){(meso-tetra(para-chloro-phenyl)porphyrinato}cadmium(II)

In this work we report the synthesis of the cadmium(II)-meso-tetra(para-chloro-phenyl)porphyrin with the morpholine O-donor axial ligand with formula [Cd(TClPP)(morph)] (I). This coordination compound adopts a distorted five-coordinate square pyramidal ge

A One-Step Route to CO2-Based Block Copolymers by Simultaneous ROCOP of CO2/Epoxides and RAFT Polymerization of Vinyl Monomers

The one-step synthesis of well-defined CO2-based diblock copolymers was achieved by simultaneous ring-opening copolymerization (ROCOP) of CO2/epoxides and RAFT polymerization of vinyl monomers using a trithiocarbonate compound bearin

Synthesis and single crystal structure of a new polymorph of 5, 10, 15, 20-tetrakis-(4-chlorophenyl) porphyrin, H2TTPCl4: Spectroscopic investigation of aggregation of H2TTPCl4

5, 10, 15, 20-tetrakis-(4-chlorophenyl) porphyrin, H2TTPCl4, has been isolated as a new polymorph following the modified Adler’s method and its X-ray crystal structure solved. The new polymorph (I) crystallises in the monoclinic spac

K2S2O8mediated synthesis of 5-Aryldipyrromethanes and meso-substituted A4-Tetraarylporphyrins

The synthesis of dipyrromethanes from pyrrole and arylglyoxylic acids in the presence of K2S2O8at 90 C is reported affording dipyrromethanes in very good yields. Unlike an excess pyrrole traditionally used in dipyrromethane synthesis, the current method uses a stoichiometric amount of pyrrole avoiding any use of Br?nsted or Lewis acid. A gram scale synthesis of 5-phenyldipyrromethane is also achieved demonstrating potential scale up of dipyrromethanes using this method feasible. Subsequently, dipyrromethanes were converted to A4tetraarylporphyrins also in the presence of K2S2O8at 90C. A direct synthesis of A4-tetraphenylporphyrin from excess pyrrole and phenylglyoxylic acid in the presence of K2S2O8 at 90C is also reported.

Efficient oxidation of cycloalkanes with simultaneously increased conversion and selectivity using O2 catalyzed by metalloporphyrins and boosted by Zn(AcO)2: A practical strategy to inhibit the formation of aliphatic diacids

The direct sources of aliphatic acids in cycloalkanes oxidation were investigated, and a strategy to suppress the formation of aliphatic acids was adopted through enhancing the catalytic transformation of oxidation intermediates cycloalkyl hydroperoxides to cycloalkanols by Zn(II) and delaying the emergence of cycloalkanones. Benefitted from the delayed formation of cycloalkanones and suppressed non-selective thermal decomposition of cycloalkyl hydroperoxides, the conversion of cycloalkanes and selectivity towards cycloalkanols and cycloalkanones were increased simultaneously with satisfying tolerance to both of metalloporphyrins and substrates. For cyclohexane, the selectivity towards KA-oil was increased from 80.1% to 96.9% meanwhile the conversion was increased from 3.83 % to 6.53 %, a very competitive conversion level with higher selectivity compared with current industrial process. This protocol is not only a valuable strategy to overcome the problems of low conversion and low selectivity lying in front of current cyclohexane oxidation in industry, but also an important reference to other alkanes oxidation.

Synthesis of meso-substituted corroles and porphyrins using iodine as a catalyst

Abstract: Different types of corroles and porphyrins are synthesized from substituted aldehydes and pyrrole. The current synthetic method involves iodine as catalyst and proceeds at room temperature itself. By varying the amounts of reactants (i.e., pyrrole and aldehydes), the corrole and porphyrins were obtained in good to excellent yields. These products were characterized by 1H-NMR, UV-visible, and HRMS techniques. The reaction approach utilizes the readily available pyrrole and substituted aldehydes as starting materials and makes this reaction highly attractive in diversity-oriented synthesis. Graphic abstract: Different types of porphyrins and corroles are synthesized from substituted aldehydes and pyrrole using iodine as a catalyst and the reaction proceeds at room temperature itself. By varying the amount of reactants (i.e. pyrrole and aldehydes), the porphyrins and corroles are obtained in good to excellent yields.[Figure not available: see fulltext.]