Cas 221130-15-0,2-[2-(<i>tert</i>-butyl-dimethyl-silanyloxy)-ethyl]-2-(3,4-dichloro-phenyl)-morpholine

221130-15-0

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Basic information

Product Name: 2-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-2-(3,4-dichloro-phenyl)-morpholine
Synonyms:
CAS NO:221130-15-0
Molecular Formula:
Molecular Weight: 390.425
EINECS: N/A
Product Categories: N/A
Mol File: 221130-15-0.mol
Article Data: 1

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 2-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-2-(3,4-dichloro-phenyl)-morpholine(CAS DataBase Reference)
NIST Chemistry Reference: 2-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-2-(3,4-dichloro-phenyl)-morpholine(221130-15-0)
EPA Substance Registry System: 2-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-2-(3,4-dichloro-phenyl)-morpholine(221130-15-0)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 221130-15-0(Hazardous Substances Data)

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221130-15-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 221130-15-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,1,1,3 and 0 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 221130-15:
(8*2)+(7*2)+(6*1)+(5*1)+(4*3)+(3*0)+(2*1)+(1*5)=60
60 % 10 = 0
So 221130-15-0 is a valid CAS Registry Number.

221130-15-0Upstream product

221130-15-0Downstream Products

191673-56-0 (R)-2-(2-(3,4-dichlorophenyl)morpholin-2-yl)ethanol

221130-15-0Relevant articles and documents

Efficient synthesis of a key intermediate of neurokinin receptor antagonists using a bifunctional asymmetric catalyst

Takamura, Makoto,Yabu, Kazuo,Nishi, Takahide,Yanagisawa, Hiroaki,Kanai, Motomu,Shibasaki, Masakatsu

, p. 353 - 356 (2007/10/03)

We report herein an efficient synthetic method for the preparation of 2-[(2R)-arylmorpholin-2-yl]ethanol, a key intermediate of neurokinin receptor antagonists. Catalytic asymmetric cyanosilylation of ketone 3 using titanium complex 4 was employed to introduce the required stereochemistry.

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