221155-02-8Relevant articles and documents
Palladium-catalyzed asymmetric intermolecular Mizoroki-Heck reaction for construction of a chiral quaternary carbon center
Zhang, Qing-Song,Wan, Shi-Li,Chen, Di,Ding, Chang-Hua,Hou, Xue-Long
, p. 12235 - 12238 (2015)
Palladium-catalyzed asymmetric intermolecular Mizoroki-Heck reaction for the construction of a chiral quaternary carbon center is developed, affording 2,2-disubstituted 2,5-dihydrofurans in high yield with excellent enantioselectivity. The products are ea
Chiral silver phosphate-catalyzed cycloisomeric kinetic resolution of α-allenic alcohols
Wang, Yan,Zheng, Kuan,Hong, Ran
, p. 4096 - 4099 (2012/04/10)
A kinetic resolution of α-allenic alcohols is realized through chiral silver phosphate-catalyzed cycloisomerization with high stereoselectivity (selectivity factor up to 189) and tolerance of a variety of functional groups. A mechanistic model is proposed to interpret the origin of the high stereoselectivity and broad substrate scope.