22120-32-7

Basic information

• Product Name: 5-CHLORO-N,N-DIMETHYLTRYPTAMINE
• Synonyms: 5-CHLORO-N,N-DIMETHYLTRYPTAMINE;1H-Indole-3-ethanaMine, 5-chloro-N,N-diMethyl-
• CAS NO: 22120-32-7
• Molecular Formula: C₁₂H₁₅ClN₂
• Molecular Weight: 222.71
• Mol File: 22120-32-7.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 363.9 °C at 760 mmHg
• Flash Point: 173.9 °C
• Appearance: /
• Density: 1.191 g/cm³
• Vapor Pressure: 1.74E-05mmHg at 25°C
• Refractive Index: 1.623
• CAS DataBase Reference: 5-CHLORO-N,N-DIMETHYLTRYPTAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-CHLORO-N,N-DIMETHYLTRYPTAMINE(22120-32-7)
• EPA Substance Registry System: 5-CHLORO-N,N-DIMETHYLTRYPTAMINE(22120-32-7)

Safety Data

• Hazardous Substances Data: 22120-32-7(Hazardous Substances Data)

Usage

General Description

5-Chloro-N,N-dimethyltryptamine, also known as 5-Cl-DMT, is a synthetic psychoactive substance similar to the well-known psychedelic compound DMT. It is a member of the tryptamine class of compounds and is structurally related to psilocybin and psilocin. 5-Cl-DMT is known for its hallucinogenic effects, which include visual and auditory distortions, altered perception of time and space, and profound changes in mood and consciousness. It is considered to be a potent and potentially dangerous drug, with limited research on its effects and safety profile. The legal status of 5-Cl-DMT varies by country, and its use is generally discouraged due to its potential for harmful side effects and unpredictable reactions.

InChI:InChI=1/C12H15ClN2/c1-15(2)6-5-9-8-14-12-4-3-10(13)7-11(9)12/h3-4,7-8,14H,5-6H2,1-2H3

Upstream product

• 161202-91-1 1-hydroxy-N,N-dimethyltryptamine 
• 3764-94-1 5-chlorotryptamine 
• 74-88-4 methyl iodide 
• 50-00-0 formaldehyd 
• 29095-44-1 2-(1H-indol-3-yl)-N,N-dimethyl-2-oxoacetamide 
• 61-50-7 N,N-dimethyltryptamine 
• 120-72-9 indole 
• 19718-92-4 4-(N,N-dimethylamino)butyraldehyde dimethyl acetal 
• 1073-70-7 4-chlorophenylhydrazine hydrochloride 
• 942-26-7 5-chlorotryptamine hydrochloride 
• 38662-17-8 2-(dihydroindol-3-yl)-N,N-dimethylethylamine 

Downstream Products

• 639808-95-0 2-[1-(2-bromobenzyl)-5-chloroindol-3-yl]ethyl-N,N-dimethylamine 
• 154323-57-6 almotriptan 

Relevant articles and documents

Indole derivatives and its application on the medicament

The invention provides indole derivatives or stereisomers, tautomers, nitrogen oxides, solvate, metabolic products, pharmaceutically acceptable salts or prodrugs thereof for treating the alzheimer disease. The invention further discloses a pharmaceutical composition containing the compounds and a method of using the compounds or the pharmaceutical composition thereof to treat the alzheimer disease.

Tryptamine derivatives as novel non-nucleosidic inhibitors against hepatitis B virus

A series of tryptamine derivatives were synthesized and evaluated for their anti-hepatitis B virus (HBV) activity and cytotoxicity in the HepG2.2.15 cell line. The preliminary SAR was discussed. Compounds 2e and 4a showed potent antiviral activity (IC50 = 0.4 and 50 = 40.6 and >25 μM, respectively).

SIMPLE SYNTHESES OF LESPEDAMINE AND 5-BROMO-N,N-DIMETHYLTRYPTAMINE BASED ON 1-HYDROXYINDOLE CHEMISTRY

Various types of 1-hydroxyindoles were prepared for the first time.Through methylation or acid catalyzed nucleophilic bromination of N,N-dimethyl-1-hydroxytryptamine, simple syntheses of lespedamine and 5-bromo-N,N-dimethyltryptamine were achieved, respectively.