22123-08-6Relevant articles and documents
A facile approach for the synthesis of novel 1,2,4-triazolo[4,3-a] pyridine derivatives in single step
Kumar, G. Santhosh,Kurumurthy,Rao, P. Sambasiva,Veeraswamy,Rao, P. Shanthan,Narsaiah
, p. 75 - 79 (2015)
A series of novel substituted 4-trifluoromethyl-pyridin-2-yl hydrazide derivatives 5 and 7-trifluoromethyl- 1,2,4-triazolo[4,3-a]pyridine derivatives 6 were synthesized through a facile method in single step from 2-hydrazino-pyridine derivatives 4 and their reaction with aliphatic/aromatic acids in the presence of POCl3 and PCl5. In each reaction, an intermediate 5 and product 6 were formed in definite proportion except in 5a, 5d, and 6e and were independent of reaction time and temperature.