22133-40-0 Usage
General Description
CHEMBRDG-BB 9071293 is a chemical compound with a molecular formula of C16H14O6. It is a derivative of the flavonoid apigenin, which is found in a variety of plants including chamomile, parsley, and celery. CHEMBRDG-BB 9071293 has been studied for its potential antioxidant and anti-inflammatory properties, as well as its potential for use in cancer therapy. Additionally, it has been investigated for its ability to inhibit the growth of cancer cells and induce apoptosis. Research on CHEMBRDG-BB 9071293 is ongoing to fully understand its potential uses and mechanisms of action in various medical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 22133-40-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,1,3 and 3 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 22133-40:
(7*2)+(6*2)+(5*1)+(4*3)+(3*3)+(2*4)+(1*0)=60
60 % 10 = 0
So 22133-40-0 is a valid CAS Registry Number.
InChI:InChI=1/C9H13NS/c1-2-7-11-9-5-3-8(10)4-6-9/h3-6H,2,7,10H2,1H3
22133-40-0Relevant articles and documents
Electrophilic Chlorine from Chlorosulfonium Salts: A Highly Chemoselective Reduction of Sulfoxides
Acosta-Guzmán, Paola,Mahecha-Mahecha, Camilo,Gamba-Sánchez, Diego
supporting information, p. 10348 - 10354 (2020/07/13)
Herein, we describe a selective late-stage deoxygenation of sulfoxides based on a novel application of chlorosulfonium salts and demonstrate a new process using these species generated in situ from sulfoxides as the source of electrophilic chlorine. The use of highly nucleophilic 1,3,5-trimethoxybenzene (TMB) as the reducing agent is described for the first time and applied in the deoxygenation of simple and functionalized sulfoxides. The method is easy to handle, economic, suitable for gram-scale operations, and readily applied for poly-functionalized molecules, as demonstrated with more than 45 examples, including commercial medicines and analogues. We also report the results of competition experiments that define the more reactive sulfoxide and we present a mechanistic proposal based on substrate and product observations.
