2215-78-3

Basic information

• Product Name: (4-PHENOXYPHENYL)METHANOL
• Synonyms: (4-PHENOXYPHENYL)METHANOL;RARECHEM AL BD 0081;4-Phenoxybenzyl alcohol 97%;(4-Phenoxyphenyl)methanol, 4-(Hydroxymethyl)diphenyl ether;4-Phenoxybenzylalcohol97%;Benzenemethanol, 4-phenoxy-
• CAS NO: 2215-78-3
• Molecular Formula: C₁₃H₁₂O₂
• Molecular Weight: 200.23
• Mol File: 2215-78-3.mol
• Article Data: 34

Chemical Properties

• Melting Point: 54.5-56°C
• Boiling Point: 333.2 °C at 760 mmHg
• Flash Point: 149.1 °C
• Appearance: /
• Density: 1.151 g/cm³
• Vapor Pressure: 5.5E-05mmHg at 25°C
• Refractive Index: 1.595
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 14.36±0.10(Predicted)
• CAS DataBase Reference: (4-PHENOXYPHENYL)METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (4-PHENOXYPHENYL)METHANOL(2215-78-3)
• EPA Substance Registry System: (4-PHENOXYPHENYL)METHANOL(2215-78-3)

Safety Data

• Statements: 43
• Safety Statements: 36/37
• Hazardous Substances Data: 2215-78-3(Hazardous Substances Data)

Usage

Uses

(4-phenoxyphenyl)methanol is a useful reactant and reagent in organic reactions and synthesis.

InChI:InChI=1/C13H12O2/c14-10-11-6-8-13(9-7-11)15-12-4-2-1-3-5-12/h1-9,14H,10H2

Upstream product

• 67-36-7 4-phenoxy benzaldehyde 
• 591-50-4 iodobenzene 
• 623-05-2 (4-hydroxyphenyl)methanol 
• 873-76-7 para-Chlorobenzyl alcohol 
• 108-95-2 phenol 
• 18282-51-4 4-iodo-benzyl alcohol 
• 873-75-6 4-bromobenzenemethanol 
• 7732-18-5 water 
• 1192-96-7 potassium p-cresolate 
• 1623-95-6 4-phenoxybenzoyl chloride 
• 1706-12-3 4-phenoxytoluene 
• 108-86-1 bromobenzene 
• 5031-78-7 4-phenoxyacetophenone 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 

Downstream Products

• 36881-42-2 1-(bromomethyl)-4-phenoxybenzene 
• 4039-92-3 4-phenoxybenzyl chloride 
• 93512-64-2 3,3,3-Trifluoro-2-methyl-2-(4-phenoxy-benzyloxy)-propionic acid 
• 93496-93-6 3,3,3-Trifluoro-2-methyl-2-(4-phenoxy-benzyloxy)-propionic acid methyl ester 
• 139259-73-7 p-phenoxybenzyl benzohydroxamate 
• 139259-88-4 p-phenoxybenzyl N-chlorobenzohydroxamate 
• 139259-92-0 N-(acetyloxy)-N-(((4-(phenyloxy)phenyl)methyl)oxy)benzamide 
• 18916-12-6 1-(phenoxy)-4-[(E)-2-phenylethenyl]benzene 
• 90296-16-5 (4-Phenoxy-benzyloxy)-acetic acid 
• 944517-44-6 4-(hydroxy(4-phenoxyphenyl)methyl)benzonitrile 
• 41616-59-5 (4-phenoxy-benzyliden)-aniline 
• 71969-48-7 4-amino-4'-phenoxy-benzophenone 
• 1706-12-3 4-phenoxytoluene 

Relevant articles and documents

PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS

This disclosure provides pharmaceutical compounds to treat medical disorders, such as complement-mediated disorders, including complement Cl -mediated disorders.

Preparation method of 4-benzyloxybenzyl alcohol

The invention relates to a preparation method of 4-benzyloxybenzyl alcohol. The preparation method comprises the specific steps: A, adding a proper amount of dimethylformamide, p-fluorobenzaldehyde, phenol, inorganic alkali and cuprous salt in a reaction kettle, stirring to rise the temperature, controlling the temperature at 100 DEG C to 150 DEG C and carrying out a reaction, after completion ofthe reaction, cooling to room temperature, filtering to remove inorganic salt, then recycling dimethylformamide, adding the obtained 4-benzyloxybenzaldehyde in methanol and dissolving; and B, adding the methanol solution of 4-benzyloxybenzaldehyde and a catalyst into a pressure kettle, controlling the temperature at 50 DEG C to 70 DEG C, introducing hydrogen and carrying out a reaction, keeping the hydrogen pressure at 5 kg/cm or more, after completion of the reaction, cooling to room temperature, filtering to remove the catalyst under anaerobic conditions, then recycling methanol, carryingout cooling crystallization of the remaining product, and thus obtaining 4-benzyloxybenzyl alcohol. The preparation method of 4-benzyloxybenzyl alcohol is simple in route and high in yield.