221654-69-9

Basic information

• Product Name: 2-Benzothiazolemethanamine,6-fluoro-alpha-methyl-,(alphaS)-(9CI)
• Synonyms: 2-Benzothiazolemethanamine,6-fluoro-alpha-methyl-,(alphaS)-(9CI);(S)-1-(6-FLUOROBENZO[D]THIAZOL-2-YL)ETHANAMINE
• CAS NO: 221654-69-9
• Molecular Formula: C9H9FN2S
• Molecular Weight: 0
• Product Categories: BENZOTHIAZOLE
• Mol File: 221654-69-9.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Benzothiazolemethanamine,6-fluoro-alpha-methyl-,(alphaS)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Benzothiazolemethanamine,6-fluoro-alpha-methyl-,(alphaS)-(9CI)(221654-69-9)
• EPA Substance Registry System: 2-Benzothiazolemethanamine,6-fluoro-alpha-methyl-,(alphaS)-(9CI)(221654-69-9)

Safety Data

• Hazardous Substances Data: 221654-69-9(Hazardous Substances Data)

Downstream Products

• 1296214-86-2 1-(4-cyanophenyl)-3-[(1R)-1-(6-fluoro-1,3-benzothiazol-2-yl)ethyl]urea 
• 1296214-83-9 1-(4-isopropylphenyl)-3-[(1R)-1-(6-fluoro-1,3-benzothiazol-2-yl)ethyl]urea 
• 1296214-84-0 1-(4-chlorophenyl)-3-[(1R)-1-(6-fluoro-1,3-benzothiazol-2-yl)ethyl]urea 
• 1296214-89-5 1-(4-nitrophenyl)-3-[(1R)-1-(6-fluoro-1,3-benzothiazol-2-yl)ethyl]urea 
• 1296214-73-7 1-[(1R)-1-(6-fluoro-1,3-benzothiazol-2-yl)ethyl]-3-phenylurea 
• 1296214-80-6 1-(3,5-dichlorophenyl)-3-[(1R)-1-(6-fluoro-1,3-benzothiazol-2-yl)ethyl]urea 
• 1296214-76-0 1-benzyl-3-[(1R)-1-(6-fluoro-1,3-benzothiazol-2-yl)ethyl]urea 
• 1296214-82-8 1-(3,5-dimethylphenyl)-3-[(1R)-1-(6-fluoro-1,3-benzothiazol-2-yl)ethyl]urea 

Relevant articles and documents

Synthesis of 1-[(1R)-1-(6-fluoro-1,3-benzothiazol-2-yl)ethyl]-3-substituted phenyl ureas and their inhibition activity to acetylcholinesterase and butyrylcholinesterase

A series of novel 1-[(1R)-1-(6-fluoro-1,3-benzothiazol-2-yl)ethyl]-3- substituted phenyl ureas were synthesized by the condensation of (1R)-1-(6-fluoro-1,3-benzothiazol-2-yl)ethanamine with substituted phenyl isocyanates under mild conditions. Their structures were confirmed 1H, 13C, and 19F NMR spectra, and elemental analyses. The optical activities were confirmed by optical rotation measurements. The inhibition activity of 1-[(1R)-1-(6-fluoro-1,3-benzothiazol-2- yl)ethyl]-3-substituted phenyl ureas to acetylcholinesterase (ACHE) and butyrylcholinesterase (BCHE) was also tested. Preliminary bioassay indicated that the target ureas displayed excellent acetylcholinesterase and butyrylcholinesterase inhibition activity.