22233-54-1

Basic information

• Product Name: 3-CHLORO-5-NITROBENZALDEHYDE
• Synonyms: 3-CHLORO-5-NITROBENZALDEHYDE;3-Chloro-5-nitrolbenzaldehyde
• CAS NO: 22233-54-1
• Molecular Formula: C₇H₄ClNO₃
• Molecular Weight: 185.56
• Mol File: 22233-54-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 281.4 °C at 760 mmHg
• Flash Point: 124 °C
• Appearance: /
• Density: 1.485 g/cm³
• Vapor Pressure: 0.00358mmHg at 25°C
• Refractive Index: 1.63
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 3-CHLORO-5-NITROBENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-CHLORO-5-NITROBENZALDEHYDE(22233-54-1)
• EPA Substance Registry System: 3-CHLORO-5-NITROBENZALDEHYDE(22233-54-1)

Safety Data

• Hazardous Substances Data: 22233-54-1(Hazardous Substances Data)

Usage

General Description

3-CHLORO-5-NITROBENZALDEHYDE is a chemical compound with the molecular formula C7H4ClNO3. It is an organic compound that contains a nitro group and a chloro group attached to a benzene ring. It is commonly used in the synthesis of various pharmaceuticals, agrochemicals, and dyes. 3-CHLORO-5-NITROBENZALDEHYDE is known for its strong yellow color and is used as a dye intermediate. It is also used as a reagent in organic synthesis for the preparation of other organic compounds. Additionally, 3-CHLORO-5-NITROBENZALDEHYDE has been found to have antimicrobial and antifungal properties, making it potentially useful in the development of new pharmaceuticals.

InChI:InChI=1/C7H4ClNO3/c8-6-1-5(4-10)2-7(3-6)9(11)12/h1-4H

Upstream product

• 16582-38-0 3-chloro-5-nitrotoluene 
• 79944-62-0 (3-chloro-5-nitrophenyl)methanol 
• 90390-46-8 (3-amino-5-nitrophenyl)methanol 
• 71022-43-0 3,5-dinitrobenzyl alcohol 
• 36138-28-0 3-chloro-5-nitro-benzoic acid methyl ester 
• 23218-93-1 3-amino-5-nitro-benzoic acid methyl ester 

Downstream Products

• 960083-35-6 4-(3-chloro-5-nitro-phenyl)-1H-pyrrole-3-carbonitrile 
• 90390-41-3 Butyl-(3-chloro-5-nitro-benzyl)-amine 
• 90390-40-2 (3-Chloro-5-nitro-benzyl)-propyl-amine 
• 90390-39-9 (3-Chloro-5-nitro-benzyl)-ethyl-amine 
• 90390-38-8 (3-Chloro-5-nitro-benzyl)-methyl-amine 
• 960083-34-5 3-(3-chloro-5-nitro-phenyl)-acrylonitrile 
• 67483-50-5 (E)-3-chloro-5,β-dinitro-styrene 
• 1615252-85-1 (S)-2,4-diamino-6-((1-(5-chloro-3-(3-chloro-5-(difluoromethyl)phenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)ethyl)amino)pyrimidine-5-carbonitrile 
• 1615254-49-3 (S)-tert-butyl 1-(5-chloro-3-(3-chloro-5-(difluoromethyl)phenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)ethylcarbamate 
• 1615256-04-6 (S)-2-(1-aminoethyl)-5-chloro-3-(3-chloro-5-(difluoromethyl)phenyl)quinazolin-4(3H)-one 

Relevant articles and documents

PYRROLE DERIVATIVES WITH CRTH2 RECEPTOR MODULATOR ACTIVITY

There are provided according to the invention compounds of formula (I) in free or salt form, wherein R3, R 4, R5, R6a, R6b, Q and W are as described in the specification, process for preparing them, a

Benzylamines: Synthesis and evaluation of antimycobacterial properties

The synthesis of benzylamines with various N-alkyl chains and substituents in the aromatic system as well as their evaluation on Mycobacterium tuberculosis H 37 Ra are described. The most active compounds in this test, N-methyl-3-chlorobenzylamine (MIC 10.2 μg/mL), N-methyl-3,5-dichlorobenzylamine (93, MIC 10.2 μg/mL), and N-butyl-3,5-difluorobenzylamine (MIC 6.4 μg/mL), also exhibited a marked inhibitory effect on Mycobacterium marinum and Mycobacterium lufu used for the determination of antileprotic properties. The combination of 93 with aminosalicylic acid, streptomycin, or dapsone exert marked supra-additive effects on M. tuberculosis H 37 Ra.