222551-24-8

Basic information

• Product Name: 2-(4-FLUORO-PHENYL)-4-METHYL-PYRIDINE
• Synonyms: 2-(4-FLUORO-PHENYL)-4-METHYL-PYRIDINE
• CAS NO: 222551-24-8
• Molecular Formula: C₁₂H₁₀FN
• Molecular Weight: 187.2129032
• Mol File: 222551-24-8.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 282.436 °C at 760 mmHg
• Flash Point: 124.613 °C
• Appearance: /
• Density: 1.112 g/cm³
• Vapor Pressure: 0.006mmHg at 25°C
• Refractive Index: 1.551
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-(4-FLUORO-PHENYL)-4-METHYL-PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-FLUORO-PHENYL)-4-METHYL-PYRIDINE(222551-24-8)
• EPA Substance Registry System: 2-(4-FLUORO-PHENYL)-4-METHYL-PYRIDINE(222551-24-8)

Safety Data

• Hazardous Substances Data: 222551-24-8(Hazardous Substances Data)

Usage

General Description

2-(4-Fluoro-phenyl)-4-methyl-pyridine is a chemical compound with the molecular formula C12H10FN and a molar mass of 193.21 g/mol. It is a substituted pyridine derivative containing a fluorine atom and a methyl group attached to the pyridine ring. 2-(4-FLUORO-PHENYL)-4-METHYL-PYRIDINE is used in the pharmaceutical and agrochemical industries as a building block for the synthesis of various biologically active compounds and agrochemicals. 2-(4-Fluoro-phenyl)-4-methyl-pyridine has potential applications in the development of new drugs and pesticides due to its unique structure and reactivity. Additionally, it is used as a reagent in organic synthesis for the preparation of complex molecules and pharmaceutical intermediates.

InChI:InChI=1/C12H10FN/c1-9-6-7-14-12(8-9)10-2-4-11(13)5-3-10/h2-8H,1H3

Upstream product

• 3678-62-4 2-chloro-4-picoline 
• 1765-93-1 4-fluoroboronic acid 
• 4926-28-7 2-Bromo-4-picoline 

Downstream Products

• 446301-94-6 2-[2-(4-fluorophenyl)pyridin-4-yl]-1-(pyridin-2-yl)ethanone 
• 1245614-29-2 2-(4'-fluorophenyl)-4-(4-methylstyryl)pyridine 
• 1245614-30-5 F-ppy-4-CH=CHC₆H₄NMe₂ 
• 222551-13-5 4-bromomethyl-2-(4-fluoro-phenyl)pyridine 

Relevant articles and documents

The new iridium(III) pyridyltetrazolate complexes for blue phosphorescence

A series of new blue-phosphorescent iridium complexes containing phenypyridine (ppy) derivatives and pyridyltetrazole were synthesized and their photophysical and electroluminescent properties were investigated. In the complex, the phenyl moiety which is

α-Halo carbonyls enable: Meta selective primary, secondary and tertiary C-H alkylations by ruthenium catalysis

A catalytic meta selective C-H alkylation of arenes is described using a wide range of α-halo carbonyls as coupling partners. Previously unreported primary alkylations with high meta selectivity have been enabled by this methodology whereas using straight chain alkyl halides affords ortho substituted products. Mechanistic analysis reveals an activation pathway whereby cyclometalation with a ruthenium(ii) complex activates the substrate molecule and is responsible for the meta selectivity observed. A distinct second activation of the coupling partner allows site selective reaction between both components.

New blue phosphorescent iridium complexes containing phenylpyridine and triazole ligands: Synthesis and luminescence studies

The synthesis and luminescence of iridium(III) complexes containing new phenylpyridine (C∧N) ligands, 4-Me-4'-F-ppy, 4-Me-4'-CF3-ppy and 4-OMe-4'-CF3-ppy, were studied. These ligands were designed for development of the blue light-em