22288-81-9 Usage
General Description
2-(Acetylamino)-3-thiophenecarboxylic acid methyl ester is a chemical compound with the molecular formula C11H11NO3S. It is a derivative of thiophene and carboxylic acid, containing an acetylamino group. The methyl ester group is also present, and it is used for the purpose of esterification. 2-(Acetylamino)-3-thiophenecarboxylicacidmethylester has potential applications in the field of organic synthesis and pharmaceuticals due to its unique structure and properties. It is important to handle and use this compound with care, following appropriate safety protocols and guidelines.
Check Digit Verification of cas no
The CAS Registry Mumber 22288-81-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,2,8 and 8 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 22288-81:
(7*2)+(6*2)+(5*2)+(4*8)+(3*8)+(2*8)+(1*1)=109
109 % 10 = 9
So 22288-81-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H9NO3S/c1-5(10)9-7-6(3-4-13-7)8(11)12-2/h3-4H,1-2H3,(H,9,10)
22288-81-9Relevant articles and documents
THIENOPYRIMIDINONE COMPOUNDS
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Paragraph 0198, (2019/10/23)
The present disclosure provides compounds that modulate protein function and/or restore protein homeostasis. The disclosure provides methods of modulating protein-mediated diseases, disorders, conditions, or responses. Compositions, including in combination with other therapeutic agents, are provided.
Opioid ligands related to tifluadom
Archer, Sydney,Seyed-Mozaffari, Ahmad,Simon, Eric J.,Gioannini, Theresa L.
, p. 569 - 572 (2007/10/02)
In an effort to prepare ligands with kappa selective affintity suitable for use in affinity chromatography, we synthesized the haloacetamido derivatives 17 and 18 of tifluadom.These compounds showed modest opioid binding affinity but were more active at the mu than at the kappa site.The nitro compounds 7 and 16 were prepared as potential intermediates.The former, a weak mu agonist, was devoid of kappa affinity (IC50 > 1E-6 M), whereas the latter was a mu selective agonist.Keywords: tifluadom/ benzodiazepines/ affinity chromathography/ opioid binding activity