22302-63-2 Usage
General Description
2-Cyano-N-naphthalen-1-yl-acetamide, often referred to by its alternate name "Acetamide, 2-cyano-N-1-naphthalenyl-", is an organic compound which falls under the chemical category of Naphthalene and Naphthalene derivatives. It is a solid substance with a molecular weight of 246.308 g/mol. The chemical formula is C15H12N2O. The compound is used in the synthesis of many other chemical compounds. It does not have any colour and does not produce any odour. The substance should be handled and stored properly to avoid any risk, as there are potential health hazards on prolonged exposure.
Check Digit Verification of cas no
The CAS Registry Mumber 22302-63-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,3,0 and 2 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 22302-63:
(7*2)+(6*2)+(5*3)+(4*0)+(3*2)+(2*6)+(1*3)=62
62 % 10 = 2
So 22302-63-2 is a valid CAS Registry Number.
InChI:InChI=1/C13H10N2O/c14-9-8-13(16)15-12-7-3-5-10-4-1-2-6-11(10)12/h1-7H,8H2,(H,15,16)
22302-63-2Relevant articles and documents
α-Cyanocinnamide derivatives: A new family of non-peptide, non-sulfhydryl inhibitors of ras farnesylation
Poradosu, Enrique,Gazit, Aviv,Reuveni, Hadas,Levitzki, Alexander
, p. 1727 - 1736 (2007/10/03)
Farnesylation of Ras and other proteins is required for their membrane attachment and normal function. Here we report on the synthesis of α-cyanocinnamide derivatives, a new family of farnesyltransferase inhibitors. These compounds are nonpeptidic and do not contain sulfhydryl groups. The most potent compound is a pure competitive inhibitor with respect to the Ras protein and mixed competitive with respect to farnesyl diphosphate. Selectivity studies against geranylgeranyltransferase and biological activities of selected compounds are described. Copyright (C) 1999.
