2236-52-4

Basic information

• Product Name: 2,2'-DIIODOBIPHENYL
• Synonyms: 2,2'-DIIODOBIPHENYL;2,2'-Diiodo-1,1'-biphenyl;1-iodo-2-(2-iodophenyl)benzene
• CAS NO: 2236-52-4
• Molecular Formula: C₁₂H₈I₂
• Molecular Weight: 406
• Product Categories: Biphenyl derivatives
• Mol File: 2236-52-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: 210-211℃
• Boiling Point: 398.1 °C at 760 mmHg
• Flash Point: 204.8 °C
• Appearance: /
• Density: 2.041 g/cm³
• CAS DataBase Reference: 2,2'-DIIODOBIPHENYL(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2'-DIIODOBIPHENYL(2236-52-4)
• EPA Substance Registry System: 2,2'-DIIODOBIPHENYL(2236-52-4)

Safety Data

• RIDADR: UN 3152 9/PG II
• HazardClass: 9
• PackingGroup: II
• Hazardous Substances Data: 2236-52-4(Hazardous Substances Data)

Usage

General Description

2,2'-DIIODOBIPHENYL is a chemical compound with the molecular formula C12H8I2. It is a halogenated biphenyl, consisting of two benzene rings linked together by a single carbon-carbon bond. 2,2'-DIIODOBIPHENYL is used as a reagent in organic synthesis, particularly in the preparation of pharmaceuticals, agrochemicals, and advanced materials. 2,2'-DIIODOBIPHENYL is also known for its high reactivity and ability to undergo various types of chemical reactions, making it a versatile building block in organic chemistry. However, it is important to handle this compound with caution, as it is toxic and can cause harm if not used properly.

Upstream product

• 615-42-9 1,2-Diiodobenzene 
• 62-53-3 aniline 
• 92-52-4 biphenyl 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 910879-01-5 2,2'-bis-(2-carboxy-phenylsulfanyl)-biphenyl 
• 16291-37-5 2,2'''''-diiodo-[1,1';2',1'';2'',1''';2''',1'''';2'''',1''''']sexiphenyl 
• 92-52-4 biphenyl 
• 114049-60-4 (9H-carbazol-9-yl)(4-methoxyphenyl)methanone 
• 314047-37-5 (4-aminophenyl)(9H-carbazol-9-yl)methanone 
• 86-74-8 9H-carbazole 
• 1196082-14-0 2,2'-bis[bis(4-hexadecyloxyphenyl)hydroxymethyl]biphenyl 
• 1196082-13-9 2,2'-bis[bis(4-octyloxyphenyl)hydroxymethyl]biphenyl 
• 5550-08-3 9,9-diphenyl-9-silafluorene 
• 873792-52-0 5,5′-dibromo-2,2′-diiodo-1,1′-biphenyl 
• 20302-14-1 9,9-diphenylfluorene 
• 37694-95-4 imidazo[1,2-f]phenanthridine 
• 530-48-3 1,1-Diphenylethylene 
• 4709-68-6 9-benzhydrylidenefluorene 

Relevant articles and documents

Convenient One-Pot Synthesis of 9 H -Carbazoles by Microwave Irradiation Employing a Green Palladium-Based Nanocatalyst

An efficient palladium-catalyzed tandem reaction for the one-pot synthesis of 9 H -carbazoles under microwave irradiation is developed. This approach involves a sequential Buchwald-Hartwig amination and a direct arylation from affordable and inexpensive anilines and 1,2-dihaloarenes. For the development of this purpose, a novel and magnetically recoverable palladium nanocatalyst supported on a green biochar under ligand-free conditions is used. Compared to other existing palladium-based protocols, the present synthetic methodology shows a drastic reduction in reaction times and excellent compatibility with different functional groups allowing to obtain a small library of 9 H -carbazoles in high yields and with good regioselectivity. This procedure represents the first example in the direct synthesis of carbazoles using a heterogeneous palladium nanocatalyst from commercial precursors. To examine the application of this protocol, a direct and scalable synthesis of the bioactive carbazole alkaloid clausenalene from commercially available starting materials is described.

Nucleophilic substitution in dibenz[b,d]iodolium and 11,12-dihydro-10H-dibenz[b,g]iodocinium cations

Treatment of dibenz[b,d]iodolium tetrafluoroborate with NO2-, Br-, and N3- ions gave, along with nucleophilic substitution products, 2-nitro-, 2-bromo-, and 2-azido-2′-iodiphenyls, diphenyl, 2-iododiphenyl, and 2,2′-diiododiphenyl (products of one electron reduction), whereas 11,12-dihydro-10H-dibenz[b,g]-iododnium tetrafluoroborate underwent nucleophilic substitution with all three nucleophiles to give a single product in each case: 1-(2-nitrophenyl)-, 1-(2-bromophenyl)-, or 1-(2-azidophenyl)-3-(2-iodophenyl)propane. 1998 Plenum Publishing Corporation.