223777-15-9 Usage
Uses
Different sources of media describe the Uses of 223777-15-9 differently. You can refer to the following data:
1. A uridine derivative as building blocks for cross-linking oligonucleotides.
2. 2'-O-(2-Methoxyethyl)uridine is a Uridine (U829910) derivative as building blocks for cross-linking oligonucleotides.
3. 2''-O-(2-Methoxyethyl)uridine is a Uridine (U829910) derivative as building blocks for cross-linking oligonucleotides.
Check Digit Verification of cas no
The CAS Registry Mumber 223777-15-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,3,7,7 and 7 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 223777-15:
(8*2)+(7*2)+(6*3)+(5*7)+(4*7)+(3*7)+(2*1)+(1*5)=139
139 % 10 = 9
So 223777-15-9 is a valid CAS Registry Number.
InChI:InChI=1/C12H18N2O7/c1-19-4-5-20-10-9(17)7(6-15)21-11(10)14-3-2-8(16)13-12(14)18/h2-3,7,9-11,15,17H,4-6H2,1H3,(H,13,16,18)/t7-,9+,10+,11-/m1/s1
223777-15-9Relevant articles and documents
Conversion of uridine into 2'-O-(2-methoxyethyl)uridine and 2'-O-(2- methoxyethyl)cytidine
Legorburu, Urtzi,Reese, Colin B.,Song, Quanlai
, p. 5635 - 5640 (1999)
Reaction between aluminium 2-methoxyethoxide and 2,2'-anhydro-1-β-D- arabinofuranosyluracil 6 gives 2'-O-(2-methoxyethyl)uridine 9 in high yield. Compound 9 is converted into 2'-O-(2-methoxyethyl)cytidine 11 in good yield.
2′-Substituted RNA preparation
-
, (2008/06/13)
A process for the preparation of a compound of formula (1): is provided, which comprises the reaction a compound of formula (2): with a compound of formula Al(OR)3 under substantially anhydrous conditions. X, and X1 are each independently H or a protecting group, B is a base; R is an alkyl, alkoxyalkyl, alkenyl or alkynyl group, each of which may be optionally substituted, and L is a leaving group.