223786-49-0 Usage
Description
1-(4-Nitrophenyl)piperidine-4-carboxamide is a chemical compound that features a piperidine ring and a carboxamide group connected to a 4-nitrophenyl moiety. It is recognized for its potential in medicinal chemistry and pharmaceutical compound synthesis, with the nitro group in its structure making it a valuable precursor for nitrogen-containing heterocycles. 1-(4-NITROPHENYL)PIPERIDINE-4-CARBOXAMIDE also shows promise in the development of new drugs for various diseases due to its potential biological activities.
Uses
Used in Medicinal Chemistry:
1-(4-Nitrophenyl)piperidine-4-carboxamide is used as a building block for the synthesis of pharmaceutical compounds, contributing to the development of new medications for a range of diseases.
Used in Pharmaceutical Compound Synthesis:
As a chemical intermediate, 1-(4-Nitrophenyl)piperidine-4-carboxamide is used in the creation of various pharmaceutical compounds, enhancing the diversity and effectiveness of available treatments.
Used in the Preparation of Nitrogen-Containing Heterocycles:
The presence of the nitro group in 1-(4-Nitrophenyl)piperidine-4-carboxamide makes it a useful precursor for the preparation of nitrogen-containing heterocycles, which are important in the field of organic chemistry and pharmaceuticals.
Used in Drug Development:
1-(4-Nitrophenyl)piperidine-4-carboxamide exhibits potential biological activities and is studied for its role in the development of new drugs, aiming to address various diseases and improve patient outcomes.
Check Digit Verification of cas no
The CAS Registry Mumber 223786-49-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,3,7,8 and 6 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 223786-49:
(8*2)+(7*2)+(6*3)+(5*7)+(4*8)+(3*6)+(2*4)+(1*9)=150
150 % 10 = 0
So 223786-49-0 is a valid CAS Registry Number.
223786-49-0Relevant articles and documents
The liquid crystal aligning agent, liquid crystal alignment film, the liquid crystal display element, phase difference film and method of manufacturing the same, polymer and compound
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Paragraph 0207; 0209-0210, (2018/02/04)
The invention provides a liquid crystal alignment agent, a liquid crystal alignment film, a liquid crystal display element, a phase different film, a method of making a phase difference film, a polymer, and a compound. The invention provides the liquid cr
Synthesis and biological activity of novel 1,4-diazepane derivatives as factor Xa inhibitor with potent anticoagulant and antithrombotic activity
Koshio, Hiroyuki,Hirayama, Fukushi,Ishihara, Tsukasa,Taniuchi, Yuta,Sato, Kazuo,Sakai-Moritani, Yumiko,Kaku, Seiji,Kawasaki, Tomihisa,Matsumoto, Yuzo,Sakamoto, Shuichi,Tsukamoto, Shin-Ichi
, p. 2179 - 2191 (2007/10/03)
Factor Xa (fXa) is a serine protease involved in the coagulation cascade, which has received great interest as a potential target for the development of new antithrombotic drugs. Herein we report a novel series of fXa inhibitors in which the 1,4-diazepane moiety was designed to interact with the S4 aryl-binding domain of the fXa active site. Compound 13 (YM-96765) showed potent fXa inhibitory activity (IC50=6.8nM) and effective antithrombotic activity without prolonging bleeding time.
