224824-30-0Relevant articles and documents
A convenient one-pot synthesis of boroxoles from diboronic acid
Lafitte, Guillaume,Kunihiro, Kana,Bonneaud, Céline,Dréan, Bénédicte,Gaigne, Frédéric,Parnet, Véronique,Pierre, Romain,Raffin, Catherine,Vatinel, Rodolphe,Fournier, Jean-Fran?ois,Musicki, Branislav,Ouvry, Gilles,Bouix-Peter, Claire,Tomas, Loic,Harris, Craig S.
, p. 3757 - 3759 (2017)
The preparation of the boroxole motif traditionally relies on a 3-step process and the use of n-butyl lithium that can limit substrate scope. Herein during our exploration toward novel RORγ inhibitors, we identified a convenient one-pot preparation of the motif in good yields with good substrate scope.
