22600-77-7 Usage
General Description
1H-Imidazol-2-ylmethylamine dihydrochloride, also known as Histamine dihydrochloride, is a chemical compound often used in medical applications and research, primarily due to its role as a histamine receptor agonist. Thus, it is widely used in studies related to allergic responses, inflammation and gastric acid secretion. It primarily interacts with H1 and H2 histamine receptors which are involved in the aforementioned physiological processes. When used in therapeutic applications, for instance in cancer treatment, it stimulates immune responses. The properties of 1H-Imidazol-2-ylmethylamine dihydrochloride - its molecular weight is roughly 184.07 g/mol, it is soluble in water, and it appears as a white to off-white crystalline powder - also make it ideal for lab-based usage.
Check Digit Verification of cas no
The CAS Registry Mumber 22600-77-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,6,0 and 0 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 22600-77:
(7*2)+(6*2)+(5*6)+(4*0)+(3*0)+(2*7)+(1*7)=77
77 % 10 = 7
So 22600-77-7 is a valid CAS Registry Number.
InChI:InChI=1/C4H7N3.2ClH/c5-3-4-6-1-2-7-4;;/h1-2H,3,5H2,(H,6,7);2*1H
22600-77-7Relevant articles and documents
NMR characterization of hydrate and aldehyde forms of imidazole-2- carboxaldehyde and derivatives
Lazaro Martinez, Juan Manuel,Romasanta, Pablo Nicolas,Chattah, Ana Karina,Buldain, Graciela Yolanda
supporting information; experimental part, p. 3208 - 3213 (2010/08/19)
The existence and stability of the aldehyde-hydrate form of imidazole-2-carboxaldehyde (4) were studied using FTIR together with solution- and solid-state NMR experiments. The results allowed us to conclude that the hydrate form was stable and precipitate
(8,9-Dihydro-7H-imidazodiazepin-5-yl)-cyanamide und homologe Imidazo-Bizyklen
Buschauer, A.,Schunack, W.
, p. 753 - 757 (2007/10/02)
The reaction of the 2-(ω-aminoalkyl)imidazoles 4a-f with N-cyanodiphenylimidocarbonate (7) leads to appropriately hydrogenated imidazoimidazoles, imidazodiazepines and imidazodiazocines (9a-f), which are similar to (7,8-dihydroimidazopyrimidin-5-yl)cyanamides (3) in respect to their chemical and spectroscopic properties.
