226990-01-8Relevant articles and documents
Antineoplastic agents. 410. Asymmetric hydroxylation of trans- combretastatin A-4
Pettit, George R.,Toki, Brian E.,Herald, Delbert L.,Boyd, Michael R.,Hamel, Ernest,Pettit, Robin K.,Chapuis, J. Charles
, p. 1459 - 1465 (2007/10/03)
The South African willow tree Combretum caffrum has yielded a number of potent cancer cell growth inhibitors. The present SAR studies of the antineoplastic agent combretastatin A-4 (1c) were focused mainly on the olefinic bridge to determine the effects o