227178-09-8

Basic information

• Product Name: 1-(3-(pyridin-2-yl)phenyl)ethan-1-one
• Synonyms: 1-(3-(pyridin-2-yl)phenyl)ethan-1-one
• CAS NO: 227178-09-8
• Molecular Weight: 197.236
• Mol File: 227178-09-8.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: 1-(3-(pyridin-2-yl)phenyl)ethan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-(pyridin-2-yl)phenyl)ethan-1-one(227178-09-8)
• EPA Substance Registry System: 1-(3-(pyridin-2-yl)phenyl)ethan-1-one(227178-09-8)

Safety Data

• Hazardous Substances Data: 227178-09-8(Hazardous Substances Data)

Usage

General Description

The chemical 1-(3-(pyridin-2-yl)phenyl)ethan-1-one is a ketone compound with a molecular formula C14H11NO. It consists of a benzene ring attached to a pyridine ring, with a ketone functional group on the ethyl chain. 1-(3-(pyridin-2-yl)phenyl)ethan-1-one has the potential to be used in various applications, including pharmaceuticals and chemical synthesis. Its structure and properties make it a valuable building block for creating more complex organic molecules. Additionally, it can be utilized as a reagent in chemical reactions due to its unique chemical properties.

Upstream product

• 13737-04-7 2-(trimethylsilyl)pyridine 
• 2142-63-4 1-(3-Bromophenyl)ethanone 
• 98-98-6 2-Picolinic acid 
• 65007-00-3 pyridin-2-yl trifluoromethanesulfonate 
• 14452-30-3 3'-iodoacetophenone 
• 1219454-89-3 2-((difluoromethyl)sulfonyl)pyridine 
• 109-04-6 2-bromo-pyridine 
• 17997-47-6 2-tri-n-butylstannylpyridine 

Downstream Products

• 1236046-64-2 C₂₀H₁₅NO₂ 
• 1379667-26-1 N-[4-acetyl-2-(pyridin-2-yl)phenyl]-4-methylbenzenesulfonamide 
• 1373350-16-3 C₃₇H₃₈N₂O 
• 1355042-73-7 2-(4-(3,5-di-tert-butylphenyl)-6-(3-(pyridin-2-yl)phenyl)pyridin-2-yl)phenol 
• 1355042-85-1 [Pt(2-(4-(3,5-di-tert-butylphenyl)-6-(3-(pyridin-2-yl)phenyl)pyridin-2-yl)phenolate)] 
• 1397290-28-6 4-acetyl-2-(pyridin-2-yl)benzonitrile 
• 1421030-10-5 1-(5-bromo-2,4-difluorophenyl)ethanone 
• 1355042-81-7 1-(5-bromo-2,4-difluorophenyl)ethanone 
• 1373350-01-6 1-(5-bromo-2,4-difluorophenyl)ethanone 
• 1334336-35-4 1-phenyl-1-(3-(pyridin-2-yl)phenyl)ethanol 
• 1093649-18-3 1-{2-oxo-2-[30-(200-pyridinyl)phenyl]ethyl}pyridinium iodide 

Relevant articles and documents

Nickel-Catalyzed Reductive 2-Pyridination of Aryl Iodides with Difluoromethyl 2-Pyridyl Sulfone

A novel nickel-catalyzed reductive cross-coupling between aryl iodides and difluoromethyl 2-pyridyl sulfone (2-PySO2CF2H) enables C(sp2)-C(sp2) bond formation through selective C(sp2)-S bond cleavage, which demonstrates the new reactivity of 2-PySO2CF2H reagent. This method employs readily available nickel catalyst and sulfones as cross-electrophile coupling partners, providing facile access to biaryls under mild reaction conditions without pregeneration of arylmetal reagents.

Access to Branched Allylarenes via Rhodium(III)-Catalyzed C-H Allylation of (Hetero)arenes with 2-Methylidenetrimethylene Carbonate

A rhodium(III)-catalyzed C-H allylation of (hetero)arenes by using 2-methylidenetrimethylene carbonate as an efficient allylic source has been developed for the first time. Five different directing groups including oxime, N-nitroso, purine, pyridine, and pyrimidine were compatible, delivering various branched allylarenes bearing an allylic hydroxyl group in moderate to excellent yields.

Mild, Selective Ru-Catalyzed Deuteration Using D2O as a Deuterium Source

A method for the selective deuteration of polyfunctional organic molecules using catalytic amounts of [RuCl2(PPh3)3] and D2O as a deuterium source is presented. Through variation of additives like CuI, KOH, and various amounts of zinc powder, orthogonal chemoselectivities in the deuteration process are observed. Mechanistic investigation indicates the presence of different, defined Ru-complexes under the given specific conditions.