228107-82-2 Usage
Description
3,5-Bis(trifluoromethyl)mandelic acid is a chemical compound characterized by the molecular formula C11H7F6O4. It is a white, crystalline solid that is distinguished by the presence of two trifluoromethyl groups, which contribute to its strong electron-withdrawing properties. These properties enhance the molecule's acidity and stability, making it a valuable reagent in organic synthesis. 3,5-BIS(TRIFLUOROMETHYL)MANDELIC ACID has been the subject of research for its potential in the development of new pharmaceuticals and agrochemicals due to its unique chemical characteristics.
Uses
Used in Pharmaceutical Industry:
3,5-Bis(trifluoromethyl)mandelic acid is used as a reagent in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs. Its unique chemical properties, including the electron-withdrawing trifluoromethyl groups, can influence the activity and stability of the resulting compounds, making it a promising candidate in drug discovery and design.
Used in Agrochemical Industry:
In the agrochemical sector, 3,5-Bis(trifluoromethyl)mandelic acid serves as a reagent in the preparation of agrochemicals. Its properties can be leveraged to enhance the effectiveness and stability of compounds used in agriculture, potentially leading to the creation of more efficient and sustainable products for crop protection and enhancement.
Used in Organic Synthesis:
3,5-Bis(trifluoromethyl)mandelic acid is utilized as a key intermediate in organic synthesis, where its electron-withdrawing trifluoromethyl groups can be strategically employed to modify the reactivity and selectivity of reactions. This makes it a versatile building block for the synthesis of complex organic molecules with potential applications in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 228107-82-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,8,1,0 and 7 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 228107-82:
(8*2)+(7*2)+(6*8)+(5*1)+(4*0)+(3*7)+(2*8)+(1*2)=122
122 % 10 = 2
So 228107-82-2 is a valid CAS Registry Number.
InChI:InChI=1/C10H6F6O3/c11-9(12,13)5-1-4(7(17)8(18)19)2-6(3-5)10(14,15)16/h1-3,7,17H,(H,18,19)
228107-82-2Relevant articles and documents
Kinetic resolution of mandelate esters via stereoselective acylation catalyzed by lipase PS-30
Chen, Peiran,Yang, Wenhong
supporting information, p. 2290 - 2294 (2014/04/17)
By using lipase PS-30 as catalyst, the kinetic resolution of a series of racemic mandelate esters has been achieved via stereoselective acylation. The value of kinetic enantiomeric ratio (E) reached up to 197.5. Substituent effect is briefly discussed.
