229976-40-3Relevant articles and documents
Efficient asymmetric synthesis of the vasopeptidase inhibitor BMS-189921
Singh, Janak,Kronenthal, David R.,Schwinden, Mark,Godfrey, Jollie D.,Fox, Rita,Vawter, Edward J.,Zhang, Bo,Kissick, Thomas P.,Patel, Bharat,Mneimne, Omar,Humora, Michael,Papaioannou, Chris G.,Szymanski, Walter,Wong, Michael K. Y.,Chen, Chien K.,Heikes, James E.,DiMarco, John D.,Qiu, Jun,Deshpande, Rajendra P.,Gougoutas, Jack Z.,Mueller, Richard H.
, p. 3155 - 3158 (2007/10/03)
(Matrix presented) An efficient asymmetric synthesis of the vasopeptidase inhibitor BMS-189921 was accomplished. Two short enantioselective syntheses of the common key intermediate (S)-α-aminoazepinone 6b were developed. Olefin 3 was converted to 6b via a
