23004-83-3

Basic information

• Product Name: Methanesulfonamide, N-(4-methoxyphenyl)-N-2-propenyl-
• CAS NO: 23004-83-3
• Molecular Formula: C11H15NO3S
• Molecular Weight: 241.311
• Mol File: 23004-83-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Methanesulfonamide, N-(4-methoxyphenyl)-N-2-propenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanesulfonamide, N-(4-methoxyphenyl)-N-2-propenyl-(23004-83-3)
• EPA Substance Registry System: Methanesulfonamide, N-(4-methoxyphenyl)-N-2-propenyl-(23004-83-3)

Safety Data

• Hazardous Substances Data: 23004-83-3(Hazardous Substances Data)

Upstream product

• 104-94-9 4-methoxy-aniline 
• 4284-48-4 N-(4-methoxyphenyl)methanesulfonamide 
• 106-95-6 allyl bromide 

Downstream Products

• 474640-46-5 4-ethoxythiocarbonylsulfanyl-5-[methanesulfonyl-(4-methoxy-phenyl)-amino]-pentanoic acid ethyl ester 
• 1609975-16-7 C₃₁H₅₂ClF₂NO₄S₃ 
• 1563063-04-6 ethyl ({4-[(4-chlorophenyl)sulfanyl]-4,4-difluoro-1-[N-(4-methoxyphenyl)methanesulfonamido]butan-2-yl}sulfanyl)methanethioate 
• 1042039-65-5 dithiocarbonic acid S-(3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-1-{[methanesulfonyl-(4-methoxy-phenyl)-amino]-methyl}-propyl) ester O-ethyl ester 
• 474640-41-0 2-benzoylamino-3-(1-methanesulfonyl-5-methoxy-2,3-dihydro-1H-indol-3-yl)-propionic acid ethyl ester 
• 474640-40-9 2-(1-methanesulfonyl-5-methoxy-2,3-dihydro-1H-indol-3-ylmethyl)-cyclohexanone 
• 73-31-4 5-methoxy-N-acetyl-tryptamine 
• 39547-16-5 3-(5-methoxy-1H-indol-3-yl)propanoic acid 
• 877082-24-1 dithiocarbonic acid (5-chloro-1-{[methanesulfonyl-(4-methoxyphenyl)-amino]-methyl}-4-oxo-pentyl) ester ethyl ester 
• 875559-65-2 benzoic acid 1-cyano-3-ethoxythiocarbonylsulfanyl-4-[methanesulfonyl-(4-methoxy-phenyl)-amino]-butyl ester 
• 474640-38-5 2-benzoylamino-4-ethoxythiocarbonylsulfanyl-5-[methanesulfonyl-(4-methoxy-phenyl)-amino]-pentanoic acid ethyl ester 
• 474640-39-6 dithiocarbonic acid O-ethyl ester S-[2-[methanesulfonyl-(4-methoxy-phenyl)-amino]-1-(1-methyl-3,6-dioxo-piperidin-2-ylmethyl)-ethyl] ester 
• 474640-37-4 dithiocarbonic acid O-ethyl ester S-[2-[methanesulfonyl-(4-methoxy-phenyl)-amino]-1-(2-oxo-cyclohexylmethyl)-ethyl] ester 
• 474640-32-9 dithiocarbonic acid O-ethyl ester S-(1-{[methanesulfonyl-(4-methoxy-phenyl)-amino]-methyl}-3-methyl-4-oxo-pentyl) ester 

Relevant articles and documents

Ultrasound-assisted one-pot three-component synthesis of new isoxazolines bearing sulfonamides and their evaluation against hematological malignancies

In the present study, following a one-pot two-step protocol, we have synthesized novel sulfonamides-isoxazolines hybrids (3a-r) via a highly regioselective 1,3-dipolar cycloaddition. The present methodology capitalized on trichloroisocyanuric acid (TCCA) as a safe and ecological oxidant and chlorinating agent for the in-situ conversion of aldehydes to nitrile oxides in the presence of hydroxylamine hydrochloride, under ultrasound activation. These nitrile oxides could be engaged in 1,3-dipolar cycloaddition reactions with various alkene to afford the targeted sulfonamides-isoxazolines hybrids (3a-r). The latter were assessed for their antineoplastic activity against model leukemia cell lines (Chronic Myeloid Leukemia, K562 and Promyelocytic Leukemia, HL-60).

S-(3-Chloro-2-oxo-propyl)-O-ethyl xanthate: A linchpin radical coupling agent for the synthesis of heterocyclic and polycyclic compounds

The preparation and use of S-(3-chloro-2-oxo-propyl)-O-ethyl xanthate to directly introduce an α-chloroketone motif is described, along with applications for the synthesis of heterocyclic and polycyclic structures. The Royal Society of Chemistry 2006.