23153-12-0

Basic information

• Product Name: 3-Chloro-4-methylsulfonylaniline
• Synonyms: 3-CHLORO-4-METHYLSULFONYLANILINE;3-Chloro-4-(methylsulphonyl)aniline;3-Chloro-4-(methylsulfonyl)phenylamine;3-Chloro-4-methanesulfonyl-aniline
• CAS NO: 23153-12-0
• Molecular Formula: C₇H₈ClNO₂S
• Molecular Weight: 205.66
• Product Categories: Amines and Anilines;Boron, Nitrile, Thio,& TM-Cpds;API intermediates
• Mol File: 23153-12-0.mol
• Article Data: 2

Chemical Properties

• Melting Point: 170-171
• Boiling Point: 423.015 °C at 760 mmHg
• Flash Point: 209.632 °C
• Appearance: /
• Density: 1.414g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.584
• Storage Temp.: 2-8°C(protect from light)
• PKA: 0.29±0.10(Predicted)
• CAS DataBase Reference: 3-Chloro-4-methylsulfonylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Chloro-4-methylsulfonylaniline(23153-12-0)
• EPA Substance Registry System: 3-Chloro-4-methylsulfonylaniline(23153-12-0)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 23153-12-0(Hazardous Substances Data)

Usage

General Description

3-Chloro-4-methylsulfonylaniline is a chemical compound with the molecular formula C7H8ClNO2S. It is an organic compound with a chlorine atom attached to the fourth carbon and a methylsulfonyl group attached to the amino group of aniline. 3-Chloro-4-methylsulfonylaniline is commonly used as a key intermediate in the synthesis of various pharmaceuticals, agrochemicals, and dyes. It is also used as a precursor for the production of other important chemicals, such as 3-chloro-4-aminobenzenesulfonic acid, which is used in the manufacture of azo and anthraquinone dyes. The presence of the chlorine and methylsulfonyl groups makes 3-Chloro-4-methylsulfonylaniline a versatile building block for the synthesis of a wide range of organic compounds with various industrial applications.

InChI:InChI=1/C7H8ClNO2S/c1-12(10,11)7-3-2-5(9)4-6(7)8/h2-4H,9H2,1H3

Upstream product

• 77146-55-5 2-chloro-1-(methylsulfanyl)-4-nitrobenzene 
• 350-30-1 3-chloro-4-fluoronitrobenzene 
• 91842-77-2 2-chloro-4-nitrophenyl methyl sulfone 

Relevant articles and documents

1-PHENYLPYRROLE COMPOUNDS

The present invention comprises a compound for the prevention and/or treatment of cardiovascular diseases, nephropathy, fibrosis, primary aldosteronism or edema. The compound is of the following general formula (I): wherein R1 represents a C1 -C3 alkyl group; R2 represents a hydroxy -C1 -C4 alkyl group and the like; R3 represents a halogeno group, a halogeno-C1 -C3 alkyl group and the like; R4 represents a hydrogen atom, a halogeno group and the like,- R5 represents a sulfamoyl group or a C1-C3 alkylsulf onyl group; R6 represents a hydrogen atom, a halogeno group and the like] or an N-oxide, atropisomer of the foregoing, or pharmaceutically acceptable salt of the foregoing.