23313-12-4

Basic information

• Product Name: L-ASCORBIC ACID 2-MONOPHOSPHATE TRI-CYCLOHEXYLAMMONIUM SALT
• Synonyms: Vitamin C phosphate;l-ascorbic acid 2-monophosphate tris-cyclohexylammonium salt;ascorbate-2-phosphate;Ascorbyl monophosphate;Ascorbyl-2-monophosphate;Ascorbyl-2-phosphate;L-Ascorbic acid, 2-(dihydrogen phosphate);MIJPAVRNWPDMOR-ZAFYKAAXSA-N
• CAS NO: 23313-12-4
• Molecular Formula: C₆H₉O₉P
• Molecular Weight: 553.64
• EINECS: 1312995-182-4
• Mol File: 23313-12-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 561.26 °C at 760 mmHg
• Flash Point: 293.239 °C
• Appearance: /
• Density: 2.013 g/cm³
• PKA: 1.38±0.10(Predicted)
• CAS DataBase Reference: L-ASCORBIC ACID 2-MONOPHOSPHATE TRI-CYCLOHEXYLAMMONIUM SALT(CAS DataBase Reference)
• NIST Chemistry Reference: L-ASCORBIC ACID 2-MONOPHOSPHATE TRI-CYCLOHEXYLAMMONIUM SALT(23313-12-4)
• EPA Substance Registry System: L-ASCORBIC ACID 2-MONOPHOSPHATE TRI-CYCLOHEXYLAMMONIUM SALT(23313-12-4)

Safety Data

• Hazardous Substances Data: 23313-12-4(Hazardous Substances Data)

Usage

General Description

L-ASCORBIC ACID 2-MONOPHOSPHATE TRI-CYCLOHEXYLAMMONIUM SALT is a chemical compound that is derived from ascorbic acid, also known as vitamin C. It is used in various industries, including pharmaceuticals, food and beverage, and cosmetics. L-ASCORBIC ACID 2-MONOPHOSPHATE TRI-CYCLOHEXYLAMMONIUM SALT is used for its antioxidant properties and its ability to promote collagen synthesis, making it a valuable ingredient in skincare products. Additionally, it also has potential applications in the treatment of certain diseases and conditions due to its anti-inflammatory and immunomodulatory effects. The tri-cyclohexylammonium salt form of L-ascorbic acid 2-monophosphate improves its solubility and bioavailability, making it easier to incorporate into various products and formulations.

Upstream product

• 50-81-7 ascorbic acid 
• 15042-01-0 O-5,6-isopropylidene-L-(+)ascorbic acid 

Downstream Products

• 50-81-7 ascorbic acid 

Relevant articles and documents

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AN IMPROVED SYNTHESIS OF L-ASCORBATE 2-POLYPHOSPHATE

L-Ascorbate (0) reacted rapidly with sodium trimetaphosphate (STMP) at 20-25 deg C and constant pH 9.5-10.0 in the presence of calcium ion.Barium and strontium ions also catalyzed the phosphorylation reaction, but not magnesium ion.The optimum reaction mixture was initially 1.4 M L-ascorbate, 1.8 M STMP, 1.7 M calcium hydroxide, and 0.4 M calcium chloride.Over a 20-min reaction period, pH was maintained by adding approximately 0.1 g calcium hydroxide in a 20percent aqueous slurry.The initial and final Ca/P ratios were ca. 0.36 and 0.42, respectively.The reaction products were 98.8percent 2-phosphorylated L-ascorbate, 1.2percent unreacted 0, and a trace of 4,5-ene, probably formed through 5,6-phosphorylated L-ascorbate 2-polyphosphate.High-performance liquid chromatography with UV detection and preparative anion-exchange chromatography showed the presence of eight 2-phosphorylated derivatives of 0 and two of the 4,5-ene skeleton.Rapid 2-phosphorylation prevented accumulation of the 4,5-elimination reaction, and three 5,6-cyclophosphoesters of 0 were found in the reaction products.A Ca/Na (3/1) salt of L-ascorbate 2-polyphosphate was isolated in 88percent yield as a white, odorless powder containing 33percent of L-ascorbate equivalents.Crystalline cyclohexylammonium salts of L-ascorbate 2-mono, di, and triphosphates were prepared.

X-Ray Analysis of L-Ascorbic Acid 2-O-Phosphate

L-Ascorbic acid 2-O-phosphate,synthesized from 5,6-O-isopropylidene L-ascorbic acid by reaction with phosphoryl chloride in alkaline water-pyridine solution, crystallized as colorless plates of the dipiperazinium salt trihydrate, C6H9O9P*2C4H10N2*3H2O.Its molecular structure was determined by X-ray analisys.Keywords--Piperazinium L-ascorbic acid 2-O-phosphate; Magnesium L-ascorbic acid 2-O-phosphate; X-ray analysis; structure determination; CMR