23361-28-6

Basic information

• Product Name: BOC-VAL-PRO-OH
• Synonyms: BOC-L-VALYL PROLINE;BOC-VAL-PRO-OH;N-BOC-L-VALYL-L-PROLINE;N-tert-Butoxycarbonyl-L-valyl-L-proline;Boc-Val-Pro;L-Proline, N-[(1,1-diMethylethoxy)carbonyl]-L-valyl-;Boc-L-Val-L-Pro-OH;-3-methylbutanoyl)
• CAS NO: 23361-28-6
• Molecular Formula: C₁₅H₂₆N₂O₅
• Molecular Weight: 314.38
• Mol File: 23361-28-6.mol
• Article Data: 19

Chemical Properties

• Melting Point: 137-138 °C
• Boiling Point: 503.2±45.0 °C(Predicted)
• Appearance: /
• Density: 1.171±0.06 g/cm3(Predicted)
• Storage Temp.: -15°C
• PKA: 3.50±0.20(Predicted)
• CAS DataBase Reference: BOC-VAL-PRO-OH(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-VAL-PRO-OH(23361-28-6)
• EPA Substance Registry System: BOC-VAL-PRO-OH(23361-28-6)

Safety Data

• Hazardous Substances Data: 23361-28-6(Hazardous Substances Data)

Usage

General Description

BOC-VAL-PRO-OH is a chemical compound that is composed of three amino acids: valine, proline, and hydroxyproline, with a Boc (tert-butoxycarbonyl) protecting group attached to the amino group of valine. BOC-VAL-PRO-OH is commonly used as a building block in peptide synthesis, where the Boc protecting group can be selectively removed to reveal the reactive amine group of valine. BOC-VAL-PRO-OH has applications in the production of pharmaceuticals, agrochemicals, and materials science, as well as in research and development. Its unique structure and reactivity make it a valuable tool for creating complex peptide sequences and scaffolds for a wide range of applications.

Upstream product

• 13734-41-3 t-Boc-L-valine 
• 147-85-3 L-proline 
• 5817-26-5 ethyl (2S)-pyrrolidine-2-carboxylate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 72-18-4 L-valine 
• 2577-48-2 methyl (2S)-pyrrolidine carboxylate 
• 58872-03-0 1--L-valyl>-L-proline phenylmethyl ester 
• 66866-46-4 C₁₅H₂₇NO₆ 
• 7364-47-8 (S)-trimethylsilyl 1-(trimethylsilyl)pyrrolidine-2-carboxylate 
• 3392-12-9 Boc-Val-ONSu 
• 38017-75-3 N-tert-butoxycarbonyl-L-valyl-L-proline methyl ester 
• 16652-71-4 benzyl (2S)-2-pyrrolidinecarboxylate hydrochloride 

Downstream Products

• 20488-27-1 (S)-1-((S)-2-Amino-3-methyl-butyryl)-pyrrolidine-2-carboxylic acid 
• 1423779-06-9 tert-butyl N-{(2S)-1-[(2S)-2-({1-[bis(2,2,2-trifluoroethoxy)phosphoryl]-2-phenylethyl}carbamoyl)pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl}carbamate 

Relevant articles and documents

Inhibition of urease enzyme activity by urea and thiourea derivatives of dipeptides conjugated 2, 3-dichlorophenyl piperazine

Objective: Studies on enzyme inhibition remain an important area of pharmaceutical research since these studies have led to the discoveries of drugs used in a variety of physiological conditions. In search of novel urease enzyme inhibitors, four dipeptide

Stereochemical basis for the anti-chlamydial activity of the phosphonate protease inhibitor JO146

JO146, a mixture of two diastereomers of a peptidic phosphonate inhibitor for Chlamydial HtrA (CtHtrA), has reported activity against Chlamydia species in both human and koala. In this study we isolated the individual diastereomers JO146-D1 and JO146-D2 (

Synthesis and antimicrobial activity of 7-Amino cephalosporanic acid derivatives of amino acids and peptides

A novel series of 7-amino cephalosporanic acid derivatives of amino acid and peptides were synthesized by solution phase technique. The synthesized compounds were tested for their biological activities against bacterial and fungal organisms. All the compounds showed potent antifungal activity and most of the compounds have shown moderate antibacterial activities. The structures of the newly synthesized compounds were confirmed by IR, 1H NMR and mass spectral analysis.