23450-18-2Relevant articles and documents
A novel spiro-functionalized polyfluorene derivative with solubilizing side chains
Vak, Doojin,Chun, Chaemin,Lee, Chang Lyoul,Kim, Jang-Joo,Kim, Dong-Yu
, p. 1342 - 1346 (2004)
We report on a new polyfluorene derivative containing a spiroanthracenefluorene unit with a remote C-10 position that provides facile substitution of alkyl groups. An ethylhexyl group was introduced into the spiroanthracenefluorene unit and the ethylhexyl
STEREORETENTIVE CROSS-COUPLING OF BORONIC ACIDS
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Paragraph 0101-0103, (2018/11/21)
The present disclosure provides tri-orthoalkylphenyl phosphine catalysts that are tuned electrically and sterically. Method of using the catalyst for cross-coupling of unactivated secondary boronic acids with near-perfect levels of site- and stereoretention are also provided.
Coupling N-H Deprotonation, C-H Activation, and Oxidation: Metal-Free C(sp3)-H Aminations with Unprotected Anilines
Evoniuk, Christopher J.,Gomes, Gabriel Dos Passos,Hill, Sean P.,Fujita, Satoshi,Hanson, Kenneth,Alabugin, Igor V.
supporting information, p. 16210 - 16221 (2017/11/22)
An intramolecular oxidative C(sp3)-H amination from unprotected anilines and C(sp3)-H bonds readily occurs under mild conditions using t-BuOK, molecular oxygen and N,N-dimethylformamide (DMF). Success of this process, which requires mildly acidic N-H bonds and an activated C(sp3)-H bond (BDE 85 kcal/mol), stems from synergy between basic, radical, and oxidizing species working together to promote a coordinated sequence of deprotonation: H atom transfer and oxidation that forges a new C-N bond. This process is applicable for the synthesis of a wide variety of N-heterocycles, ranging from small molecules to extended aromatics without the need for transition metals or strong oxidants. Computational results reveal the mechanistic details and energy landscape for the sequence of individual steps that comprise this reaction cascade. The importance of base in this process stems from the much greater acidity of transition state and product for the 2c,3e C-N bond formation relative to the reactant. In this scenario, selective deprotonation provides the driving force for the process.
