2373-23-1Relevant articles and documents
FORMULATIONS OF PROPRANOLOL AND ANALOGS AS AN AMORPHOUS MELT OR IONIC LIQUID FOR TRANSDERMAL DRUG DELIVERY
-
Paragraph 0088, (2018/07/04)
Melts or ionic liquids containing amorphous propranolol, topical formulations and patches for transdermal drug delivery, and methods of making and using thereof are described herein. The melts or ionic liquids may be in a topical drug delivery formulation or patch to be applied to the skin. The drug delivery formulation or patch contains a sufficient amount of the amorphous propranolol to deliver a therapeutically effective amount of the amorphous propranolol to the patient in need of treatment, such as for the treatment or amelioration of infantile hemangioma. The formulations have a low viscosity and reduced skin irritation compared to the crystalline propranolol free base (PFB). The melts or ionic liquids can be formed by a salt metathesis reaction.
Novel sulphosuccinates and detergent compositions containing them
-
, (2008/06/13)
The invention provides novel dialkyl sulphosuccinates in which one alkyl group is C6 and the other is C8, both alkyl groups preferably being straight chain. The soluble salts of these materials are useful detergents, exhibiting outstandingly good foaming performance, and may be used, for example, in shampoos, fabric washing compositions and, in particular, manual dishwashing compositions.