23746-80-7

Basic information

• Product Name: 1H-Indole, 5-chloro-2-(4-chlorophenyl)-
• CAS NO: 23746-80-7
• Molecular Formula: C14H9Cl2N
• Molecular Weight: 262.138
• Mol File: 23746-80-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1H-Indole, 5-chloro-2-(4-chlorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole, 5-chloro-2-(4-chlorophenyl)-(23746-80-7)
• EPA Substance Registry System: 1H-Indole, 5-chloro-2-(4-chlorophenyl)-(23746-80-7)

Safety Data

• Hazardous Substances Data: 23746-80-7(Hazardous Substances Data)

Usage

Molecular structure

An organic compound consisting of an indole ring with a chlorine atom at the 5th position and a phenyl ring with a chlorine atom at the 4th position.

Usage

Commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals due to its versatile reactivity and structural features.

Biological activities

Known for its diverse biological activities, including antimicrobial, antifungal, and anticancer properties.

Synthesis of heterocyclic compounds

Used as a starting material in the synthesis of various heterocyclic compounds.

Chemical reactivity

Can undergo various chemical reactions to form new derivatives with potentially valuable properties.

Applications in material science and organic electronics

Has potential applications due to its unique electronic and optical properties.

Upstream product

• 106-39-8 bromochlorobenzene 
• 17422-32-1 5-chloro-1H-indole 
• 106-47-8 4-chloro-aniline 
• 937-20-2 p-chlorophenacyl chloride 
• 99273-17-3 4-chloro-N-(4-chloro-2-methylphenyl)benzamide 
• 19158-57-7 (2-(4-chlorophenyl)-2-oxoethyl)dimethylsulfonium bromide 

Downstream Products

• 837-58-1 2-amino-4'-chloro-5-chlorobenzophenone 
• 104384-25-0 5-chloro-2-(4-chlorophenyl)-1H-indole-3-carbaldehyde 
• 117616-10-1 5-chloro-2-(4-chlorophenyl)-1-methyl-1H-indole 

Relevant articles and documents

Pd/β-cyclodextrin-catalyzed C-H functionalization in water: A greener approach to regioselective arylation of (NH)-indoles with aryl bromides

A greener and more practical strategy for the site-selective C-H arylation of (NH)-indoles via coupling of (hetero)aryl bromides was developed, in which β-cyclodextrin, acting as both a ligand for Na2PdCl4 and a host for indoles, enables the reactions to occur easily in water. The key advantage of this method is the ingenious merging of aqueous homogeneous catalysis and ligand mediation, leading to the highly regioselective formation of C3-arylindoles with a broad substrate scope and functional-group tolerance. Moreover, the regioselectivity can be switched from the C3 to the C2-position by varying the nature of the base without recourse to employing ArI as substrates.

N,N-Dialkyl-2-phenylindol-3-ylglyoxylamides. A New Class of Potent and Selective Ligands at the Peripheral Renzodiazepine Receptor

We report the synthesis and the affinity data at both the peripheral (PBR) and the central benzodiazepine receptors of a series of N,N-dialkyl-2-phenylindol-3-ylglyoxylamide derivatives III, designed as conformationally constrained analogues of 2-phenylin

Synthesis of 2-Arylindoles via Aza-ring Closure of Sulphonium Salts

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