238098-26-5

Basic information

• Product Name: 2-methyl-4-（1,1,1,2,3,3,3-heptafluoro-2-propyl）aniline
• Synonyms: 2-methyl-4-（1,1,1,2,3,3,3-heptafluoro-2-propyl）aniline;2-Methyl-4-heptafluoroisopropylaniline;Benzenamine, 2-methyl-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-;4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2-methylaniline
• CAS NO: 238098-26-5
• Molecular Formula: C₁₀H₈F₇N
• Molecular Weight: 275.17
• Mol File: 238098-26-5.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 200 ºC
• Flash Point: 83 ºC
• Appearance: /
• Density: 1.401
• Vapor Pressure: 0.335mmHg at 25°C
• Refractive Index: 1.424
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• Solubility: Chloroform (Slightly), DMSO (Slightly)
• PKA: 2.52±0.10(Predicted)
• CAS DataBase Reference: 2-methyl-4-（1,1,1,2,3,3,3-heptafluoro-2-propyl）aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-4-（1,1,1,2,3,3,3-heptafluoro-2-propyl）aniline(238098-26-5)
• EPA Substance Registry System: 2-methyl-4-（1,1,1,2,3,3,3-heptafluoro-2-propyl）aniline(238098-26-5)

Safety Data

• Hazardous Substances Data: 238098-26-5(Hazardous Substances Data)

Usage

Uses

2-Methyl-4-(1,1,1,2,3,3,3-heptafluoro-2-propyl)aniline is a useful research chemical.

InChI:InChI=1/C10H8F7N/c1-5-4-6(2-3-7(5)18)8(11,9(12,13)14)10(15,16)17/h2-4H,18H2,1H3

Upstream product

• 422-77-5 2-bromo-1,1,1,2,3,3,3-heptafluoropropane 
• 95-53-4 o-toluidine 
• 238098-38-9 heptafluoroisopropyl-3-methyl-4-nitrobenzene 
• 677-69-0 perfluoroisopropyl iodide 
• 1634-04-4 tert-butyl methyl ether 

Downstream Products

• 346575-66-4 3-iodo-N-(4-heptafluoroisopropyl-2-methylphenyl)phthalimide 
• 371771-01-6 N₂-[1,1-dimethyl-2-(methylthio)ethyl]-N₁-{2-methyl-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl}-1,2-benzenedicarboxamide 
• 371771-07-2 N-(2-methyl-4-heptafluoroisopropylphenyl)-N₂-(1,1-dimethyl-2-methylsulfonylethyl)-(1,2-benzene formamide) 
• 1126745-45-6 2-methyl-4-(1,2,2,2-tetrafluoro-1-trifluoromethylethyl)-6-thiocyanatophenylamine 
• 1616562-33-4 C₂₂H₂₀F₇N₃O₄S 
• 1616562-32-3 C₂₂H₂₀ClF₇N₂O₂S 
• 1616562-31-2 C₂₂H₂₀F₈N₂O₂S 
• 272452-68-3 C₂₂H₂₀F₇IN₂O₂S 
• 1568940-16-8 2-(1-((6-chloropyridin-3-yl)methyl)-8-nitro-5-oxo-1,2,3,5,6,7-hexahydroimidazo[1,2-a]pyridin-6-yl)-N-(2-methyl-4-(perfluoropropan-2-yl)phenyl)acetamide 
• 476311-56-5 1,3-dihydro-7-iodo-3-{2-methyl-4-[1,2,2,2-tetrafluoro-1-(trifluoro-methyl)ethyl]phenylimino}-2-benzofuran-1-one 

Relevant articles and documents

Synthesis and Insecticidal Activity of New Quinoline Derivatives Containing Perfluoropropanyl Moiety

A series of new quinoline derivatives containing perfluoropropanyl moiety were designed and synthesized. Their structures were confirmed by 1H-NMR, MS, and elemental analysis. The bioassay results showed that compound 4e exhibited good insecticidal activity against Plutella xylostella and Mythimna separata at 100?mg/L.

Novel Friedel-Crafts reaction method and catalyst thereof

The present invention relates to a novel method for preparing or synthesizing an acylated or alkylated aryl compound, such as acylated or alkylated benzene, through a reaction called Friedel-Crafts, and a novel catalyst for the method. The present invention particularly relates to a novel environment-friendly method for synthesizing the Friedel-Crafts reaction of the acylated or alkylated compound.

Synthesis and fungicidal activities of perfluoropropan-2-yl-based novel quinoline derivatives

A series of novel perfluoropropan-2-yl-based quinoline derivatives was designed and synthesized utilizing tebufloquin as the lead compound. The structures of all the newly synthesized compounds were confirmed by spectroscopic data 1HNMR, MS and elemental analysis. The results of bioassay indicated that these compounds exhibited potent fungicidal activities against Erysiphe graminis. Especially, compound 8c displayed excellent activity with EC50 value at 1.48 mg / L, which was better than that of the commercialized fungicide-tebufloquin. The structure-activity relationship for these new compounds was also discussed.