2387-59-9

Basic information

• Product Name: S-Carboxymethyl-L-cysteine
• Synonyms: carbocistein;mucodyne;S-CARBOXYMETHYL-L-CYSTEINE;2-amino-3-(carboxymethylthio)propionic acid;2-azanyl-3-(carboxymethylsulfanyl)propanoic acid;Broncodeterge
• CAS NO: 2387-59-9
• Molecular Formula: C5H9NO4S
• Molecular Weight: 179.19
• EINECS: 246-934-4
• Mol File: 2387-59-9.mol
• Article Data: 14

Chemical Properties

• Melting Point: 205.5°C
• Boiling Point: 417.3 °C at 760 mmHg
• Flash Point: 206.2 °C
• Appearance: /solid
• Density: 1.315 (estimate)
• Vapor Pressure: 2.74E-07mmHg at 25°C
• Refractive Index: 1.5216 (estimate)
• Water Solubility: SOLUBLE IN COLD WATER
• CAS DataBase Reference: S-Carboxymethyl-L-cysteine(CAS DataBase Reference)
• NIST Chemistry Reference: S-Carboxymethyl-L-cysteine(2387-59-9)
• EPA Substance Registry System: S-Carboxymethyl-L-cysteine(2387-59-9)

Safety Data

• Safety Statements: S24/25:
• Hazardous Substances Data: 2387-59-9(Hazardous Substances Data)

Usage

Uses

Mucolytic.

Brand name

Loviscol (Wyeth-Ayerst); Mucofan (Wyeth-Ayerst).

InChI:InChI=1/C5H9NO4S/c1-6-3(4(7)8)2-11-5(9)10/h3,6H,2H2,1H3,(H,7,8)(H,9,10)/t3-/m0/s1

Upstream product

• 52-90-4 L-Cysteine 
• 64-69-7 Iodoacetic acid 
• 3926-62-3 sodium monochloroacetic acid 
• 2150-55-2 2-amino-⁽²⁾-thiazoline-4-carboxylic acid 
• 10318-18-0 DL-cysteine hydrochloride 
• 7732-18-5 water 
• 79-11-8 chloroacetic acid 
• 56-89-3 L-cystine 
• 90237-73-3 α-Chlor-β-<(methoxycarbonylmethyl)thio>propansaeure-methylester 
• 88347-79-9 α-Azido-β-<(methoxycarbonylmethyl)thio>propansaeure-methylester 
• 407-41-0 L-phosphoserine 
• 68-11-1 mercaptoacetic acid 
• 52-89-1 l-cysteine hydrochloride 
• 5147-00-2 O-acetyl-L-serine 

Downstream Products

• 5439-87-2 S-Carboxymethyl-L-cysteine-sulfoxide 
• 112246-66-9 S-Carboxymethyl-L-cysteine-(4S)-sulfoxide 
• 61475-35-2 S-Carboxymethyl-L-cysteine-(4R)-sulfoxide 
• 14226-97-2 L-5-oxo-thiomorpholine-3-carboxylic acid 
• 26177-54-8 N-Acetyl-S-carboxymethyl-L-cysteine 
• 100719-46-8 N-Benzoyl-S-methoxycarbonylmethyl-L-cystein-S,S-dioxid-methylester 
• 100193-42-8 N-Benzoyl-S-carboxymethyl-L-cystein-S,S-dioxid 

Relevant articles and documents

Preparation method of carbocisteine

The invention discloses a preparation method of carbocisteine. The preparation method comprises the three steps of condensation reaction, neutralization and crystallization, and recrystallization. Through adding carbonate and an antioxidant to a reaction system and strictly controlling reaction conditions, the content of impurity amino acid in a finished product is reduced substantially, and the purity and the product quality of carbocisteine are improved. The preparation method has the advantages of simplicity in operation, short production cycle, low cost, and the like.

Cystine Diamide Analogs for the Prevention of Cystine Stone Formation in Cystinuria

Cystine analogs that improve the solubility of L-cystine in urine for treatment of cystinuria and which have the structure: and pharmaceutically acceptable salts, solvates and prodrugs thereof, wherein each R and R′ pair are independently selected from (i) or (ii);(i) R and R′ are independently selected from hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alcohol, substituted or unsubstituted aryl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocyclic, and substituted or unsubstituted heteroaryl, or(ii) R and R′ together form a substituted or unsubstituted heterocyclic ring structure, or a substituted or unsubstituted heteroaryl ring structure;X is hydrogen, or an alkyl; and Y is O or S.