23906-13-0Relevant articles and documents
Synthesis, characterization and in vitro antimicrobial evaluation of some novel hydrazone derivatives bearing pyrimidinyl and pyrazolyl moieties as a promising heterocycles
Kamal, Raj,Kumar, Vipan,Bhardwaj, Vikas,Kumar, Vikas,Aneja, Kamal Rai
, p. 2551 - 2560 (2015)
In the present investigation, ten new 2-((3-aryl-1-phenyl-1H-pyrazol-4-yl)methylene)-1-(4,6-dimethylpyrimidin-2-yl)hydrazine (3a-j) having pyrimidinyl and pyrazolyl moieties were synthesized. Structures of all compounds were confirmed by their spectral and elemental data. Most of the tested compounds were found to be significantly more effective against bacterial strains Staphylococcus aureus, Bacillus subtilis and Pseudomonas aeruginosa than the reference drug ciprofloxacin. All the newly synthesized compounds were found to be more potent antifungal agents than reference drug against Candida albicans, whereas except 3e all other compounds also shown good activity against Saccharomyces cerevisiae.
Solvatochromic behavior of a pyrene-pyrimidine-based Schiff base and detection of heavy metal ions in aqueous media
Ghosh, Swadesh,Singharoy, Dipti,Konar, Saugata,Naskar, Jnan Prakash,Bhattacharya, Subhash Chandra
, p. 1272 - 1283 (2021/03/26)
The synthesis and solvatochromic behavior of pyrimidine based Schiff-base (PYPH) were studied to develop a fluorescent chemo sensor for the detection of Hg2+ in aqueous solution. The characterization of PYPH was investigated on the basis of UV–vis, FTIR, 1H-NMR and mass spectral data. PYPH displays selective fluorescent turn-off response to Hg2+ in aqueous solution. The sensitivity and selectivity of PYPH toward Hg2+ among different metal ions was examined by absorption, fluorescence, 1H-NMR and mass spectral studies. Binding stoichiometry (2:1) has been confirmed by a Job’s plot, HRMS spectral studies and 1H-NMR analysis. A low detection limit was 4.2 × 10?6 M for Hg2+. Ground state geometry of PYPH has been optimized using density functional theory (DFT). These results demonstrate that PYPH has promise to detect Hg2+ ion in environmental analysis systems.
A spectroscopic exploration of the influence of charge donor group on ESIPT process and its consequences in a salicylimine
Makhal, Subhash Chandra,Bhattacharyya, Arghyadeep,Ghosh, Soumen,Guchhait, Nikhil
, p. 138 - 146 (2018/03/21)
Photophysical properties of a newly designed synthetic compound DYMDAP have been investigated in combination with computational calculations. DYMDAP shows a solvent dependent emissive behavior which in non-polar solvents shows two distinct peaks along wit