23967-97-7

Basic information

• Product Name: 3-AMINO-4-METHYLTHIOPHENE
• Synonyms: 3-AMINO-4-METHYLTHIOPHENE;3-ThiophenaMine, 4-Methyl-;4-METHYLTHIOPHEN-3-AMINE(WXG00499)
• CAS NO: 23967-97-7
• Molecular Formula: C₅H₇NS
• Molecular Weight: 113.18078
• Mol File: 23967-97-7.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 246.7 °C at 760 mmHg
• Flash Point: 103 °C
• Appearance: /
• Density: 1.161g/cm³
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 4.12±0.10(Predicted)
• CAS DataBase Reference: 3-AMINO-4-METHYLTHIOPHENE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-4-METHYLTHIOPHENE(23967-97-7)
• EPA Substance Registry System: 3-AMINO-4-METHYLTHIOPHENE(23967-97-7)

Safety Data

• Hazardous Substances Data: 23967-97-7(Hazardous Substances Data)

Usage

General Description

3-Amino-4-methylthiophene is a chemical compound with the molecular formula C5H7NS. It is a heterocyclic organic compound that contains a thiophene ring with an amino group and a methyl group. This chemical is commonly used in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds due to its reactivity and versatility. Its unique chemical structure makes it valuable in the production of a variety of compounds that are used in a wide range of industries. Additionally, 3-amino-4-methylthiophene has potential applications in materials science and has been studied for its electronic and optical properties.

Upstream product

• 616-44-4 3-Methylthiophene 
• 30318-99-1 3-bromo-4-methylthiophene 
• 85006-31-1 3-amino-4-methyl-2-thiophenecarboxylic acid methyl ester 
• 23968-18-5 3-amino 4-methylthiophene-2-carboxylic acid 

Downstream Products

• 953044-73-0 1-(4-(2-(5-(3-methylthieno[3,2-b]pyridin-7-ylthio)-3-phenoxypyridin-2-ylamino)thiazol-4-yl)piperidin-1-yl)ethanone 
• 953045-90-4 3-methylthieno[3,2-b]pyridin-7-ol 
• 953045-91-5 7-chloro-3-methylthieno[3,2-b]pyridine 
• 1393718-94-9 4-(3-amino-4-methylthiophen-2-yl)benzonitrile 
• 1393718-95-0 2-(4-methoxyphenyl)-4-methylthiophen-3-amine 
• 24030-00-0 3-amino-4-methylthiophene hydrochloride 
• 1246226-59-4 4-methyl-2-(4-trifluoromethylphenyl)-thiophen-3-ylamine 
• 1246226-70-9 4-methyl-2-p-tolylthiophen-3-ylamine 

Relevant articles and documents

C-H Amination of Arenes with Hydroxylamine

This Letter describes the development of a TiIII-mediated reaction for the C-H amination of arenes with hydroxylamine. This reaction is applied to a variety of electron-rich (hetero)arene substrates, including a series of natural products and pharmaceuticals. It offers the advantages of mild conditions (room temperature), fast reaction rates (30 min), compatibility with ambient moisture and air, scalability, and the use of inexpensive commercial reagents.

PROCESS FOR PREPARING 4-METHYL-3-THIENYLAMINE HYDROCHLORIDE

This invention is related to a process for preparing 3-amino-4-methylthiophene hydrochloride.

PROCESS FOR THE PREPARATION OF BENZIMIDAZOL THIENYLAMINE COMPOUNDS AND DERIVATIVES THEREOF USEFUL AS SODIUM/PROTON EXCHANGER TYPE 3 INHIBITORS

The present invention is an improved process for the preparation of a sodium/proton exchange inhibitor of sub-type 3 (NHE-3) useful in the treatment of sleep apnea and other related respiratory disorders. The improved synthesis of the NHE-3 inhibitor, mor