2397-26-4

Basic information

• Product Name: N-(chloro(phenyl)Methylene)-N-MethylMethanaMiniuM chloride
• Synonyms: N-(chloro(phenyl)Methylene)-N-MethylMethanaMiniuM chloride
• CAS NO: 2397-26-4
• Molecular Formula: C₉H₁₁ClN*Cl
• Molecular Weight: 204.09634
• Mol File: 2397-26-4.mol
• Article Data: 19

Chemical Properties

• Melting Point: 124-125 °C
• Appearance: /
• CAS DataBase Reference: N-(chloro(phenyl)Methylene)-N-MethylMethanaMiniuM chloride(CAS DataBase Reference)
• NIST Chemistry Reference: N-(chloro(phenyl)Methylene)-N-MethylMethanaMiniuM chloride(2397-26-4)
• EPA Substance Registry System: N-(chloro(phenyl)Methylene)-N-MethylMethanaMiniuM chloride(2397-26-4)

Safety Data

• Hazardous Substances Data: 2397-26-4(Hazardous Substances Data)

Upstream product

• 611-74-5 N,N-dimethylbenzamide 

Downstream Products

• 724-92-5 N-cicloesil-α-ossofenilacetamide 
• 6748-91-0 methyl 2,3-di-O-benzoyl-4,6-O-benzylidene-α-D-glucopyranoside 
• 15038-71-8 methyl 2-O-benzyl-4,6-O-benzylidene-α-D-glucopyranoside 
• 2774-19-8 methyl 3-O-benzyl-4,6-O-benzylidene-α-D-glucopyranoside 
• 7177-79-9 methyl 2,3-di-O-benzyl-4,6-O-benzylidene-α-D-glucopyranoside 
• 33535-04-5 methyl 3-O-benzoyl-4,6-O-benzylidene-α-D-glucopyranoside 
• 76303-17-8 methyl 2-O-benzoyl-4,6-O-benzylidene-3-O-selenobenzoyl-α-D-glucopyranoside 
• 76303-16-7 methyl 4,6-O-benzylidene-2,3-di-O-selenobenzoyl-α-D-glucopyranoside 
• 72209-40-6 Thiobenzoic acid O-((2R,3S,5R,6S)-4-acetylamino-2,5-dimethoxy-4,6-dimethyl-tetrahydro-pyran-3-yl) ester 
• 62008-66-6 1-(5α-cholestan-3β-yl)-1-phenylmethylenedimethylammonium chloride 
• 143034-48-4 dimethyl 2-(trichloromethyl)-6-phenylpyrimidine-4,5-dicarboxylate 
• 93715-03-8 ({[1-Dimethylamino-1-phenyl-meth-(E)-ylidene]-phosphanyl}-phenyl-methylene)-dimethyl-ammonium; chloride 
• 15482-60-7 N,N-dimethylthiobenzamide 
• 81827-02-3 ent-1α,13-diacetoxy-10-hydroxy-3β-thiobenzoyloxy-20-norgibberell-16-ene-7,19-dioic acid 7-methyl ester 19,10-lactone 

Relevant articles and documents

Investigations in 2,3′-biquinoline series 24. Synthesis of 3-hetarylquinolines and their 1,4-dihydro derivatives under conditions of the Vilsmeier reaction

Methods have been developed for the synthesis of 2,3′-biquinolines, their 1′,4′-dihydro derivatives, 3-pyrid-2-ylquinolines, and 3-pyrazin-2-ylquinoline based on the interaction of hetarylethylenes and vinyl butyl ether with imidoyl chlorides and Vilsmeie

A One-Pot Synthesis of Highly Functionalized Purines

Highly substituted purines were synthesized in good to high yields through a one-pot straightforward metal-free scalable method, using the Traube synthesis adapted to Vilsmeier-type reagents. From 5-amino-4-chloropyrimidines, new 9-aryl-substituted chloropurines and intermediates for peptide nucleic acid synthesis were prepared. Variant procedures allowing a rapid synthesis of ribonucleosides and 7-benzylpurine from 5-amidino-6-aminopyrimidines are also reported to illustrate the high potential of this versatile toolbox. This route appears to be particularly interesting in the field of nucleic acids for a direct and rapid access to various new 8-alkylpurine nucleosides.

Polycyclic N-heterocyclic compounds. Part 86: Synthesis and evaluation of antiplatelet aggregation activity of 2,4-disubstituted 9-chloro-5,6-dihydropyrimido[5,4-d]benzazepine and related compounds

Libraries of tricyclic 2-substituted 4-alkylamino-9-chloro-5,6-dihydropyrimido[5,4-d]benzazepines and tetracyclic 12-substituted 8-chloro-1,2,5,6-tetrahydro-4H-imidazo[1',2':1,6]pyrimido[5,4-d]benzazepines were synthesized as part of our research to develop new effective antiplatelet drugs. Several alkyl and aryl groups were used as substituents at the 2-position. Evaluation of the effects of the newly synthesized compounds on collagen-induced platelet aggregation revealed several promising antiplatelet candidates with potencies superior to aspirin.