240426-63-5Relevant articles and documents
A new method for the generation and cyclization of iminyl radicals via the Hudson reaction
Lin, Xichen,Stien, Didier,Weinreb, Steven M.
, p. 637 - 639 (1999)
(Matrix presented) A mild new synthetic procedure has been developed for in situ generation and cyclization of iminyl radicals onto pendant alkenes, followed by functionalization of the resulting carbon radical by one of a variety of trapping reagents. The key process in the method involves production of the iminyl radical via treatment of an aldoxime or ketoxime with readily available 2,6-dimethylbenzenesulfinyl chloride at -50°C to room temperature (Hudson reaction).
