24165-66-0

Basic information

• Product Name: 1-(2-CHLOROPHENYL)-3-BUTEN-1-OL 97
• Synonyms: 1-(2-CHLOROPHENYL)-3-BUTEN-1-OL 97;1-(2-chlorophenyl)but-3-en-1-ol;1-(2-Chlorophenyl)-3-buten-1-ol 97%
• CAS NO: 24165-66-0
• Molecular Formula: C₁₀H₁₁ClO
• Molecular Weight: 182.64674
• Mol File: 24165-66-0.mol
• Article Data: 60

Chemical Properties

• Melting Point: 31-35 °C(lit.)
• Boiling Point: 273.3 °C at 760mmHg
• Flash Point: >230 °F
• Appearance: /
• Density: 1.137 g/cm³
• Vapor Pressure: 0.00282mmHg at 25°C
• Refractive Index: 1.55
• PKA: 13.85±0.20(Predicted)
• CAS DataBase Reference: 1-(2-CHLOROPHENYL)-3-BUTEN-1-OL 97(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-CHLOROPHENYL)-3-BUTEN-1-OL 97(24165-66-0)
• EPA Substance Registry System: 1-(2-CHLOROPHENYL)-3-BUTEN-1-OL 97(24165-66-0)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 24165-66-0(Hazardous Substances Data)

Usage

General Description

1-(2-Chlorophenyl)-3-buten-1-ol can be prepared by the allylation of o-benzaldehyde with allyl bromide, mediated by tin/iodine system in water.

InChI:InChI=1/C10H11ClO/c1-2-5-10(12)8-6-3-4-7-9(8)11/h2-4,6-7,10,12H,1,5H2

Upstream product

• 24850-33-7 allyltributylstanane 
• 89-98-5 2-chloro-benzaldehyde 
• 1730-25-2 allylmagnesium bromide 
• 556-56-9 allyl iodid 
• 762-72-1 allyl-trimethyl-silane 
• 7393-43-3 tetraallyl tin 
• 2622-05-1 allylmagnesium bromide 
• 17849-38-6 2-Chlorobenzyl alcohol 
• 106-95-6 allyl bromide 
• 591-87-7 Allyl acetate 
• 18854-66-5 tris(allyl)aluminum 
• 107-05-1 3-chloroprop-1-ene 
• 13911-49-4 allyltriethyllead 

Downstream Products

• 80735-94-0 1-Phenyl-3-buten-1-ol 
• 22339-44-2 2,3-dihydro-3-methyl-1H-inden-1-ol 
• 1026779-15-6 (E)-1-chloro-2-(3-methoxybut-1-enyl)benzene 
• 1332954-50-3 (S)-1-(2-chlorophenyl)but-3-enyl benzoate 
• 1332954-55-8 (R)-1-(2-chlorophenyl)but-3-enyl benzoate 
• 1453859-71-6 (Z)-1-(2-chlorophenyl)but-2-en-1-one 
• 1313028-19-1 (E)-1-(2-chlorophenyl)but-2-en-1-one 
• 30543-15-8 rac-4-(2-chlorophenyl)-4-hydroxybutan-2-one 
• 20766-37-4 (E)-4-(2-chlorophenyl)-3-buten-2-one 

Relevant articles and documents

Palladium-catalyzed anti-Markovnikov oxidative acetalization of activated olefins with iron(iii) sulphate as the reoxidant

This paper discloses the efficient palladium-catalyzed anti-Markovnikov oxidative acetalization of activated terminal olefins with iron(iii) sulfate as the reoxidant. This methodology requires mild reaction conditions and shows high regioselectivity toward anti-Markovnikov products and compatibility with a wide range of functional groups. Iron(iii) sulphate was the sole reoxidant used in this method. Various olefins like vinylarenes, aryl-allylethers, aryl or benzyl acrylates and homoallylic alcohols all reacted well providing anti-Markovnikov acetals, some of which represent orthogonally functionalized 1,3- and 1,4-dioxygenated compounds.

Cp2TiCl2-Catalyzed Photoredox Allylation of Aldehydes with Visible Light

A Barbier-type Cp2TiCl2-mediated (10 mol %) photoredox allylation of aldehydes under irradiation with visible light (blue light-emitting diodes (LEDs), 450 nm) and in the presence of an organic dye (3DPAFIPN, 5 mol %) with allylbromides is described.

BICYCLIC KETONE COMPOUNDS AND METHODS OF USE THEREOF

The invention provides novel compounds having the general formula (I): (I) wherein R1, the A ring and the B ring are as described herein, pharmaceutical compositions including the compounds, and methods of using the compounds.