24280-78-2

Basic information

• Product Name: (2R,5S)-2,3,3,4,4,5-Hexafluoro-tetrahydro-furan
• CAS NO: 24280-78-2
• Molecular Weight: 180.05
• Mol File: 24280-78-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,5S)-2,3,3,4,4,5-Hexafluoro-tetrahydro-furan(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,5S)-2,3,3,4,4,5-Hexafluoro-tetrahydro-furan(24280-78-2)
• EPA Substance Registry System: (2R,5S)-2,3,3,4,4,5-Hexafluoro-tetrahydro-furan(24280-78-2)

Safety Data

• Hazardous Substances Data: 24280-78-2(Hazardous Substances Data)

Upstream product

• 374-33-4 3,3,4,4-tetrafluorooxolane 

Relevant articles and documents

Monofluorination of fluorinated oxolanes with high-valency metal fluorides

Fluorinated oxolanes were fluorinated by high-valency metal fluorides (HVMFs) such as AgF2,MnF3,CoF3,HgF2 and KCoF4 in a batch system. The fluorination reactivities of these reagents with 3,3,4,4-tetrafluoro-oxolane (4F) and 2,3,3,4,4-pentafluoro-oxolane (5F) follow the order CoF3 > AgF2 > MnF3, KCoF4 Gt; HgF2. The order of fluorination reactivities with 4F and 5F agrees with that of oxidation hypothesis [R.D. Fowler et al., Industrial and Engineering Chemistry, 39 (3) 1947, 343; J. Burdon, I.W. Parsons, J.C. Tatlow, Tetrahedron, 28 (1972) 43]. In monofluorination of 5F with CoF3, AgF2 and MnF3, fluorination of -CH2-unit was major. In a flow system, monofluorination of 4F with CoF3 was successfully achieved by diluting CoF3 with CoF2.