24309-97-5

Basic information

• Product Name: N-(2-hydroxyethyl)acetoacetamide
• Synonyms: Acetoacet-N-hydroxyethylamide;beta-(N-Acetoacetylamino)ethanol;N-(2-Hydroxyethyl)-3-oxobutanamide;N-(2-hydroxyethyl)-3-keto-butyramide;N-(2-Hydroxy-ethyl)-3-oxo-butyramide
• CAS NO: 24309-97-5
• Molecular Formula: C₆H₁₁NO₃
• Molecular Weight: 145.1564
• EINECS: 246-149-7
• Mol File: 24309-97-5.mol
• Article Data: 3

Chemical Properties

• Melting Point: 104-106 °C
• Boiling Point: 373.7 °C at 760 mmHg
• Flash Point: 179.8 °C
• Appearance: Yellow to brownisch solidifed melt
• Density: 1.132 g/cm³
• Vapor Pressure: 4.11E-07mmHg at 25°C
• Refractive Index: 1.459
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 11.48±0.46(Predicted)
• CAS DataBase Reference: N-(2-hydroxyethyl)acetoacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-hydroxyethyl)acetoacetamide(24309-97-5)
• EPA Substance Registry System: N-(2-hydroxyethyl)acetoacetamide(24309-97-5)

Safety Data

• Hazardous Substances Data: 24309-97-5(Hazardous Substances Data)

Usage

Chemical Properties

Yellow to brownisch solidifed melt

Uses

N-(2-Hydroxyethyl)acetoacetamide is used as intermediate for the syntheses of different organic chemicals, e.g. quinoxaline derivatives. Product Data Sheet

InChI:InChI=1/C6H11NO3/c1-5(9)4-6(10)7-2-3-8/h8H,2-4H2,1H3,(H,7,10)

Upstream product

• 5394-63-8 2,2,6-trimethyl-4H-1,3-dioxin-4-one 
• 141-43-5 ethanolamine 
• 674-82-8 4-methyleneoxetan-2-one 
• 78-96-6 3-amino-2-propanol 

Downstream Products

• 103293-20-5 1,4-dihydro-N-(2-hydroxyethyl)-6-methyl-4-(3-nitrophenyl)-2-phenyl-5-pyrimidinecarboxamide 
• 103294-27-5 N-(2-hydroxyethyl)-6-methyl-4-(3-nitrophenyl)-2-phenyl-5-pyrimidinecarboxamide 
• 103294-28-6 N-(2-chloroethyl)-6-methyl-4-(3-nitrophenyl)-2-phenyl-5-pyrimidinecarboxamide 
• 103293-47-6 N-(2-hydroxyethyl)-2-(3-nitrophenylmethylene)-3-oxo-butanamide 
• 273-09-6 benzofurazan 
• 6639-86-7 2-methylquinoxaline 1,4-dioxide 
• 23696-28-8 olaquindox 
• 40156-73-8 N,N'-dihydroxybenzimidazolinone 
• 74003-63-7 3‐methylquinoxaline‐2‐carboxylic acid 
• 112158-56-2 2-methyl-3-quinoxaline 1-oxide 
• 13670-39-8 1-(4,5-dihydrooxazol-2-yl)propan-2-one 
• 26244-73-5 7-methyl-3,4-dihydro-2H-[1,4]oxazepin-5-one 

Relevant articles and documents

Fe(III) Complex Compounds For The Treatment And Prophylaxis Of Iron Deficiency Symptoms And Iron Deficiency Anemias

The invention relates to iron(III) complex compounds and pharmaceutical compositions comprising them for the use as medicaments, in particular for the treatment and/or prophylaxis of iron deficiency symptoms and iron deficiency anemias.

6-FLUORO-7-(1-PIPERAZINYL)QUINOXALINE 1,4-DIOXIDES. PART I. 2-(N-2-HYDROXYALKYLCARBAMOYL) DERIVATIVES

A series of N--β-aminoalkanol 1,4-dioxides (12a-h) have been synthesized for bioassay via the Beirut reaction of 5(6)-fluoro-6(5)-(4-methyl-1-piperazinyl)benzofuroxan (9) with the appropriate N-acetoacetyl-β-aminoalkanol in the presence of triethylamine.Preliminary in vitro investigations have indicated that none of the title compounds exhibits any significant antibacterial potency at concentrations /= 200 μg/ml.