24318-43-2

Basic information

• Product Name: p-methoxybenzyl p-anisate
• Synonyms: p-methoxybenzyl p-anisate;4-Methoxybenzoic acid 4-methoxybenzyl ester;Ai3-18958;Benzoic acid, 4-methoxy-, (4-methoxyphenyl)methyl ester;Einecs 246-159-1
• CAS NO: 24318-43-2
• Molecular Formula: C₁₆H₁₆O₄
• Molecular Weight: 272.29584
• EINECS: 246-159-1
• Mol File: 24318-43-2.mol
• Article Data: 76

Chemical Properties

• Boiling Point: 413.2°C at 760 mmHg
• Flash Point: 183.1°C
• Appearance: /
• Density: 1.153g/cm³
• Vapor Pressure: 4.89E-07mmHg at 25°C
• Refractive Index: 1.555
• CAS DataBase Reference: p-methoxybenzyl p-anisate(CAS DataBase Reference)
• NIST Chemistry Reference: p-methoxybenzyl p-anisate(24318-43-2)
• EPA Substance Registry System: p-methoxybenzyl p-anisate(24318-43-2)

Safety Data

• Hazardous Substances Data: 24318-43-2(Hazardous Substances Data)

Usage

General Description

P-methoxybenzyl p-anisate, also known as 4-methoxyphenylmethyl 4-methoxybenzoate, is an organic compound commonly used in the synthesis of various chemicals and pharmaceuticals. It is a benzyl ester of p-anisic acid, and is often employed as a reagent in organic synthesis due to its ability to participate in a wide range of chemical reactions. This chemical is known for its excellent stability and solubility in a variety of solvents, making it a valuable building block in the production of fragrances, flavorings, and pharmaceuticals. It is also widely used in the field of organic chemistry as a protective group for hydroxyl and amino functionalities in chemical synthesis. Additionally, p-methoxybenzyl p-anisate is used in the production of various industrial and consumer products, where it serves as a key ingredient in the formulation of dyes, pigments, and other specialty chemicals.

InChI:InChI=1/C16H16O4/c1-18-14-7-3-12(4-8-14)11-20-16(17)13-5-9-15(19-2)10-6-13/h3-10H,11H2,1-2H3

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 100-07-2 4-methoxy-benzoyl chloride 
• 105-13-5 4-Methoxybenzyl alcohol 
• 617-86-7 triethylsilane 
• 104-93-8 p-methylanizole 
• 104-88-1 4-chlorobenzaldehyde 
• 97-95-0 2-ethyl-1-butanol 
• 100-51-6 benzyl alcohol 
• 349-95-1 4-(trifluoromethyl)benzylic alcohol 
• 17849-38-6 2-Chlorobenzyl alcohol 
• 105-30-6 2-methylpentan-1-ol 
• 612-16-8 (2-methoxyphenyl)methanol 
• 75-84-3 2,2-dimethyl-propanol-1 
• 123-51-3 i-Amyl alcohol 

Downstream Products

• 100-09-4 4-methoxybenzoic acid 
• 127866-65-3 5-[(4-methoxybenzyl)sulfanyl]-1-phenyl-1H-tetrazole 

Relevant articles and documents

Discriminating non-ylidic carbon-sulfur bond cleavages of sulfonium ylides for alkylation and arylation reactions

A sulfonium ylide participated alkylation and arylation under transition-metal free conditions is described. The disparate reaction pattern allowed the separate activation of non-ylidic S-alkyl and S-aryl bond. Under acidic conditions, sulfonium ylides serve as alkyl cation precursors which facilitate the alkylations. While under alkaline conditions, cleavage of non-ylidic S-aryl bond produces O-arylated compounds efficiently. The robustness of the protocols were established by the excellent compatibility of wide variety of substrates including carbohydrates.

N-Heterocyclic Carbene Catalyzed Ester Synthesis from Organic Halides through Incorporation of Oxygen Atoms from Air

Oxygenation reactions with molecular oxygen (O2) as the oxygen source provides a green and straightforward strategy for the construction of O-containing compounds. Demonstrated here is a novel N-heterocyclic carbene (NHC) catalyzed oxidative transformation of simple and readily available organic halides into valuable esters through the incorporation of O-atoms from O2. Mechanistic studies prove that the deoxy Breslow intermediate generated in situ is oxidized to a Breslow intermediate for further transformation by this oxidative protocol. This method broadens the field of NHC catalysis and promotes oxygenation reactions with O2.

Dual utility of a single diphosphine-ruthenium complex: A precursor for new complexes and, a pre-catalyst for transfer-hydrogenation and Oppenauer oxidation

The diphosphine-ruthenium complex, [Ru(dppbz)(CO)2Cl2] (dppbz = 1,2-bis(diphenylphosphino)benzene), where the two carbonyls are mutually cis and the two chlorides are trans, has been found to serve as an efficient precursor for the synthesis of new complexes. In [Ru(dppbz)(CO)2Cl2] one of the two carbonyls undergoes facile displacement by neutral monodentate ligands (L) to afford complexes of the type [Ru(dppbz)(CO)(L)Cl2] (L = acetonitrile, 4-picoline and dimethyl sulfoxide). Both the carbonyls in [Ru(dppbz)(CO)2Cl2] are displaced on reaction with another equivalent of dppbz to afford [Ru(dppbz)2Cl2]. The two carbonyls and the two chlorides in [Ru(dppbz)(CO)2Cl2] could be displaced together by chelating mono-anionic bidentate ligands, viz. anions derived from 8-hydroxyquinoline (Hq) and 2-picolinic acid (Hpic) via loss of a proton, to afford the mixed-tris complexes [Ru(dppbz)(q)2] and [Ru(dppbz)(pic)2], respectively. The molecular structures of four selected complexes, viz. [Ru(dppbz)(CO)(dmso)Cl2], [Ru(dppbz)2Cl2], [Ru(dppbz)(q)2] and [Ru(dppbz)(pic)2], have been determined by X-ray crystallography. In dichloromethane solution, all the complexes show intense absorptions in the visible and ultraviolet regions. Cyclic voltammetry on the complexes shows redox responses within 0.71 to -1.24 V vs. SCE. [Ru(dppbz)(CO)2Cl2] has been found to serve as an excellent pre-catalyst for catalytic transfer-hydrogenation and Oppenauer oxidation.