24343-32-6

Basic information

• Product Name: 2-(2-hydroxy-3-phenoxypropyl)-1H-isoindole-1,3(2H)-dione
• Synonyms: 1H-Isoindole-1,3(2H)-dione, 2-(2-hydroxy-3-phenoxypropyl)-; N-(2-Hydroxy-3-phenoxypropyl)phthalimide
• CAS NO: 24343-32-6
• Molecular Formula: C₁₇H₁₅NO₄
• Molecular Weight: 297.3053
• Mol File: 24343-32-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 505.2°C at 760 mmHg
• Flash Point: 259.3°C
• Density: 1.333g/cm³
• Vapor Pressure: 4.98E-11mmHg at 25°C
• Refractive Index: 1.63
• CAS DataBase Reference: 2-(2-hydroxy-3-phenoxypropyl)-1H-isoindole-1,3(2H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-hydroxy-3-phenoxypropyl)-1H-isoindole-1,3(2H)-dione(24343-32-6)
• EPA Substance Registry System: 2-(2-hydroxy-3-phenoxypropyl)-1H-isoindole-1,3(2H)-dione(24343-32-6)

Safety Data

• Hazardous Substances Data: 24343-32-6(Hazardous Substances Data)

Usage

Chemical class

Isoindole derivative

Structural components

Hydroxyphenyl group
Phenoxypropyl group

Pharmacological properties

Anti-inflammatory effects
Anti-oxidant effects

Preclinical study results

Potential as an anti-tumor agent

Potential applications

Development of new drugs for various medical conditions

Upstream product

• 4769-73-7 (RS)-1-chloro-3-phenyloxy-2-propanol 
• 1074-82-4 potassium phtalimide 
• 51918-37-7 N-(2-oxo-3-phenoxy-propyl)-phthalimide 
• 136918-14-4 phthalimide 
• 122-60-1 Phenyl glycidyl ether 

Downstream Products

• 24343-33-7 N-(2-acetoxy-3-phenoxy)propylphthalimide 

Relevant articles and documents

Synthesis of β-phthalimido-alcohols via regioselective ring opening of epoxide by using reusable basic magnetic nano particles and their biological investigation

In this work, tetra butyl ammonium hydroxide ([Bu4N]OH) and magnetic nano particles (Fe3O4@SiO2@CH2)3NH2) were introduced as efficient catalysts for the regioselective ring openi

An expedient chemo-enzymatic method for the synthesis of optically active masked 1,2-amino alcohols

The expedient synthesis of enantiopure masked 1,2-amino alcohols (ee >99%) including their alkyl substituted analogues has been achieved by the regioselective ring opening of epoxides using phthalimide, followed by highly efficient kinetic resolution under mild and environmentally friendly conditions. The addition of co-solvents during kinetic resolution significantly improved the enantioselectivity with reduction in time.