243467-60-9

Basic information

• Product Name: 1H-Indole-5-carboxylic acid, 1-(4-fluorophenyl)-
• CAS NO: 243467-60-9
• Molecular Formula: C15H10FNO2
• Molecular Weight: 255.248
• Mol File: 243467-60-9.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 1H-Indole-5-carboxylic acid, 1-(4-fluorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-5-carboxylic acid, 1-(4-fluorophenyl)-(243467-60-9)
• EPA Substance Registry System: 1H-Indole-5-carboxylic acid, 1-(4-fluorophenyl)-(243467-60-9)

Safety Data

• Hazardous Substances Data: 243467-60-9(Hazardous Substances Data)

Usage

Molecular weight

273.26 g/mol
The mass of one mole of 1H-Indole-5-carboxylic acid, 1-(4-fluorophenyl)is 273.26 grams.

Derivative of indole

Heterocyclic organic compound
The compound is derived from indole, which is an organic compound containing a heterocyclic ring (a ring containing at least one non-carbon atom).

Carboxylic acid group

Functional group
The compound contains a carboxylic acid group (-COOH), which is a functional group consisting of a carbonyl group (C=O) and a hydroxyl group (-OH) bonded to the same carbon atom.

4-Fluorophenyl group

Functional group
The compound contains a 4-fluorophenyl group (a phenyl ring with a fluorine atom at the 4-position), which is a halogenated aryl group.

Building block for synthesis

Pharmaceutical, agrochemical, and other organic compounds
1H-Indole-5-carboxylic acid, 1-(4-fluorophenyl)is commonly used as a starting material or intermediate in the synthesis of various chemical products, including pharmaceuticals, agrochemicals, and other organic compounds.

Valuable intermediate

Production of various chemical products
Due to its unique properties and structure, 1H-Indole-5-carboxylic acid, 1-(4-fluorophenyl)is a valuable intermediate in the production of a wide range of chemical products.

Upstream product

• 1144523-66-9 methyl 1-(4-fluorophenyl)-1H-indole-5-carboxylate 
• 352-34-1 4-fluoro-1-iodobenzene 
• 1011-65-0 5-methoxycarbonylindole 
• 138900-18-2 1-(4-fluorophenyl)-5-cyano-1H-indole 
• 460-00-4 1-Bromo-4-fluorobenzene 

Downstream Products

• 330944-13-3 N,N-dimethyl-1-(4-fluorophenyl)-1H-indole-5-carboxamide 
• 1252777-85-7 C₂₆H₂₆FN₅O₂S 
• 1373356-16-1 1-(4-fluorophenyl)-5-({3-[1-(1,3-thiazol-2-ylcarbonyl)piperidin-4-yl]azetidin-1-yl}carbonyl)-1H-indole 
• 1252765-13-1 JNJ-42226314 
• 1429022-30-9 1-(4-fluorophenyl)-5-({3-[4-(1,3-thiazol-2-ylcarbonyl)piperazin-1-yl]azetidin-1-yl}carbonyl)-1H-indole hydrochloride 
• 1429022-29-6 (1-(4-fluorophenyl)-1H-indol-5-yl)(3-(piperazin-1-yl)azetidin-1-yl)methanone 
• 243467-31-4 1-(2-{4-[1-(4-fluorophenyl)-5-[(1-methyl-1H-1,2,3,4-tetrazol-5-yl)methyl]-1H-indol-3-yl]-1,2,3,6-tetrahydropyridin-1-yl}ethyl)-2-imidazolidinone 
• 243467-32-5 1-(2-{4-[1-(4-fluorophenyl)-5-[(2-methyl-2H-1,2,3,4-tetrazol-5-yl)methyl]-1H-indol-3-yl]-1,2,3,6-tetrahydropyridin-1-yl}ethyl)-2-imidazolidinone 
• 330944-21-3 1-(4-Fluorophenyl)-3-[1-[2-(2-imidazolidinon-1-yl)ethyl]-4-piperidinyl]-N-methyl-1H-indole-5-carboxamide 
• 243467-24-5 1-(4-fluorophenyl)-5-[(2-methyl-2H-1,2,3,4-tetrazol-5-yl)methyl]-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole 
• 243467-23-4 1-(4-fluoro-phenyl)-5-(1-methyl-1H-tetrazol-5-ylmethyl)-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole 
• 330944-15-5 1-(4-fluorophenyl)-N-methyl-3-(1,2,3,6-tetrahydro-4-pyridyl)-1H-indole-5-carboxamide 
• 330944-17-7 1-(4-fluorophenyl)-N-methyl-3-(piperidin-4-yl)-1H-indole-5-carboxamide 
• 330944-18-8 N,N-dimethyl-1-(4-fluorophenyl)-3-(piperidin-4-yl)-1H-indole-5-carboxamide 

Relevant articles and documents

PIPERAZINE DERIVATIVES AS MAGL INHIBITORS

The invention provides new heterocyclic compounds having general Formula (I), or a pharmaceutically acceptable salt thereof, wherein R1, R2, X, Y1 and Y2 are as described herein, compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds.

MONOACYLGLYCEROL LIPASE INHIBITORS FOR THE TREATMENT OF METABOLIC DISEASES AND RELATED DISORDERS

Disclosed are compounds, compositions and methods for treating metabolic diseases, including obesity and diabetes, and for reducing weight gain. Such compounds are represented by formula (I) as follows: wherein Y and Z are defined herein.

DI-AZETIDINYL DIAMIDE AS MONOACYLGLYCEROL LIPASE INHIBITORS

Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula (I) as follows: wherein Q and Z are defined herein.