2437-17-4Relevant articles and documents
Method for preparing 6-hydroxyl-1-naphthoic acid
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Paragraph 0035; 0037; 0038-0039; 0041; 0043; 0045; 0047, (2018/12/13)
The invention discloses a method for preparing 6-hydroxyl-1-naphthoic acid and belongs to the technical field of organic synthesis. The method comprises the steps: subjecting furoic acid and methylphenyl ether, which serve as starting raw materials, to a reaction in the presence of Lewis acid, so as to prepare 6-methoxy-1-naphthoic acid; carrying out removal with the Lewis acid without separationto remove methyl, thereby preparing the high-purity 6-hydroxyl-1-naphthoic acid in a high-yield manner, wherein the purity of 6-hydroxyl-1-naphthoic acid reaches up to 98.0%. The method has the advantages that the source of the raw materials is wide, the process flow is simple and convenient, the corrosiveness to equipment is low, and pilot test proves that the industrial production is facilitated.