2437-61-8

Basic information

• Product Name: 1-Butanone, 1-(2,3,4-trihydroxyphenyl)-
• CAS NO: 2437-61-8
• Molecular Formula: C10H12O4
• Molecular Weight: 196.203
• Mol File: 2437-61-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-Butanone, 1-(2,3,4-trihydroxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Butanone, 1-(2,3,4-trihydroxyphenyl)-(2437-61-8)
• EPA Substance Registry System: 1-Butanone, 1-(2,3,4-trihydroxyphenyl)-(2437-61-8)

Safety Data

• Hazardous Substances Data: 2437-61-8(Hazardous Substances Data)

Usage

Solvent in chemical processes

Used as a solvent in various chemical reactions and processes.

Precursor in pharmaceutical production

Serves as a starting material for the synthesis of pharmaceuticals and other synthetic organic compounds.

Anti-cancer properties

Investigated for its potential to combat cancer cells.

Antioxidant properties

Explored for its ability to neutralize harmful free radicals and prevent oxidative damage.

Upstream product

• 141-75-3 butyryl chloride 
• 87-66-1 2-hydroxyresorcinol 
• 107-92-6 butyric acid 
• 106-31-0 butanoic acid anhydride 

Downstream Products

• 14503-28-7 2.3.4-Trihydroxy-1-butyl-benzol 

Relevant articles and documents

An efficient chemo-enzymatic approach towards variably functionalized benzotropolones

An efficient three-step synthesis for benzotropolones via three catalytic steps is presented. Pyrogallol phenones are formed in the first step starting from pyrogallol, which is acylated by proton-catalysis. Catalytic hydrogenation of the phenones yields the corresponding alkylated pyrogallyl dervatives. In the final enzyme-catalyzed step the pyrogallol derivatives are annulated to form the benzotropolone cores. An alternative pathway via the Pechmann reaction is also presented. The combination of the three catalytic steps gives access to a wide range of benzotropolone congeners.

AN ELEGANT SYNTHESIS OF 6-BUTYRYLCHROMANS AND CHROMENES

Condensation of hydroxybutyrophenones viz., 2,3,4-trihydroxy- (1), 2,4-dihydroxy- (3) and 2,4-dihydroxy-3-methyl- (6) butyrophenones with 2-methyl-1,3-butadiene in the presence of orthophosphoric acid affords 6-butyrylchromans which can be dehydrogenated to 6-butyrylchromenes.