2441-41-0

Basic information

• Product Name: PALMITOYL GLYCINE
• Synonyms: N-palmitoylglycine;2-palMitaMidoacetic acid;Hexadecanoylaminoacetic acid;PalGly;Palmitoyl-glycine≥ 99% (TLC)
• CAS NO: 2441-41-0
• Molecular Formula: C₁₈H₃₅NO₃
• Molecular Weight: 313.48
• Mol File: 2441-41-0.mol
• Article Data: 24

Chemical Properties

• Melting Point: 121 °C(Solv: acetone (67-64-1))
• Boiling Point: 491.8°Cat760mmHg
• Flash Point: 251.2°C
• Appearance: white to off-white/
• Density: 0.96g/cm³
• Vapor Pressure: 5.13E-11mmHg at 25°C
• Refractive Index: 1.467
• Storage Temp.: 2-8°C
• Solubility: DMSO: >10mg/mL
• PKA: 3.59±0.10(Predicted)
• CAS DataBase Reference: PALMITOYL GLYCINE(CAS DataBase Reference)
• NIST Chemistry Reference: PALMITOYL GLYCINE(2441-41-0)
• EPA Substance Registry System: PALMITOYL GLYCINE(2441-41-0)

Safety Data

• WGK Germany: 2
• Hazardous Substances Data: 2441-41-0(Hazardous Substances Data)

Usage

Chemical Properties

White to off-white powder

InChI:InChI=1/C18H35NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-17(20)19-16-18(21)22/h2-16H2,1H3,(H,19,20)(H,21,22)

Upstream product

• 14464-31-4 palmitic acid N-succinimide ester 
• 56-40-6 glycine 
• 6000-44-8 sodium glycinate 
• 112-67-4 n-hexadecanoyl chloride 
• 544-31-0 2-(palmitoylamino)ethanol 
• 57-10-3 1-hexadecylcarboxylic acid 
• 214706-34-0 N-hexadecanoyl glycine methyl ester 
• 1206591-90-3 N-palmitoyl-Gly-OtBu 
• 111-57-9 N-stearoylethanolamine 
• 142-78-9 N-(2-hydroxyethyl)dodecanamide 
• 142-58-5 myristic monoethanolamide 
• 7112-02-9 N‐(2‐hydroxyethyl)octanamide 
• 7726-08-1 decanoic acid monoethanolamide 
• 59660-78-5 N-palmitoyl-glycine ethyl ester 

Downstream Products

• 133848-35-8 N-palmitoyl-glycine amide 

Relevant articles and documents

Enzymic synthesis, physicochemical, and cell activity of glucosyl ester derivatives based on N-fatty acyl amino acid

Series of glucosyl esters derivatives were synthesized by enzymatic acylation and some surface properties, and cell activity were calculated and tested. The antitumor activity in vitro against three cancer cells, human colon carcinoma (K562), human hepatoma (HepG2), and human breast adenocarcinoma (MCF-7) of compounds, were evaluated using MTT methods. The glucosyl esters could significantly displayed high anticancer activity. Thereinto, compounds 12 and 12′ showed higher inhibition effect to cancer cells than others. Several compounds were more active than control drug 5-FU. The structure–activity relationship analysis revealed that lipophilic properties might be essential parameter for their activity.

HUMAN MICROBIOTA DERIVED N-ACYL AMIDES FOR THE TREATMENT OF HUMAN DISEASE

The present invention provides compositions and methods for the modulation of G protein-coupled receptors (GPCRs). The invention provides a genetically engineered cell, wherein the cell expresses a human microbial N-acyl synthase (hm-NAS) gene. In one embodiment, the hm-NAS gene is N-acyl serinol synthase. The invention provides a probiotic composition, the probiotic composition comprises a genetically engineered cell of the invention. The invention provides a method for modulating a G protein-coupled receptor (GPCR) activity in a subject, the method comprises administering to the subject an effective amount of a composition comprising at least one selected from the group consisting of a genetically engineered cell, an hm-NAS gene, and a N-acyl amide.

Lipid dipeptide and gel

A gelator that includes a lipid peptide of Formula (1) wherein R1 is a C9-23 aliphatic group, R2 is a hydrogen atom or a C1-4 alkyl group optionally having a C1-2 branched chain, R3 is a —(CH2)n—X group, n is a number from 1 to 4, and X is an amino group, a guanidino group, a —CONH2 group, or a 5-membered ring optionally having 1 to 3 nitrogen atoms, a 6-membered ring optionally having 1 to 3 nitrogen atoms, or a fused heterocycle including a 5-membered ring and a 6-membered ring that optionally has 1 to 3 nitrogen atoms; or a pharmaceutically usable salt of the lipid peptide.