24522-41-6

Basic information

• Product Name: N-[4-chloro-3-(trifluoromethyl)phenyl]-2-cyano-acetamide
• Synonyms: N-[4-chloro-3-(trifluoromethyl)phenyl]-2-cyano-acetamide
• CAS NO: 24522-41-6
• Molecular Weight: 262.619
• Mol File: 24522-41-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-[4-chloro-3-(trifluoromethyl)phenyl]-2-cyano-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[4-chloro-3-(trifluoromethyl)phenyl]-2-cyano-acetamide(24522-41-6)
• EPA Substance Registry System: N-[4-chloro-3-(trifluoromethyl)phenyl]-2-cyano-acetamide(24522-41-6)

Safety Data

• Hazardous Substances Data: 24522-41-6(Hazardous Substances Data)

Upstream product

• 372-09-8 cyanoacetic acid 
• 320-51-4 4-chloro-3-trifluoromethyl-aniline 
• 105-56-6 ethyl 2-cyanoacetate 

Downstream Products

• 1127247-84-0 C₁₀H₅ClF₃N₃O₂ 

Relevant articles and documents

THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS

New Antiviral Drugs and Uses thereof. The present invention relates to a new class of compounds of formula (I) having an antiviral effect and the uses thereof.

3,4-Disubstituted isothiazoles: Novel potent inhibitors of VEGF receptors 1 and 2

Novel derivatives of isothiazoles are described as potent ATP-competitive inhibitors of vascular endothelial growth factor receptors I and II (VEGFR-1/2). A number of compounds exhibited VEGFR-2 inhibitory activity comparable to that of Vatalanib in both HTRF enzymatic and cellular assays. Several derivatives featuring bulky meta-substituents in the amide portion of the molecule displayed 4- to 8-fold specificity for VEGFR-2 versus VEGFR-1. Active molecules also showed high intrinsic permeability (>30 × 10-5 cm/min) across Caco-2 cell monolayer.