245538-31-2Relevant articles and documents
The opioid μ agonist/δ antagonist DIPP-NH2[Ψ] produces a potent analgesic effect, no physical dependence, and less tolerance than morphine in rats
Schiller, Peter W.,Fundytus, Marian E.,Merovitz, Lisa,Weltrowska, Grazyna,Nguyen, Thi M.-D.,Lemieux, Carole,Chung, Nga N.,Coderre, Terence J.
, p. 3520 - 3526 (2007/10/03)
Opioid compounds with mixed μ agonist/δ antagonist properties are expected to be analgesics with low propensity to produce tolerance and dependence. In an effort to strengthen the μ agonist component of the mixed μ agonist/δ antagonist H-Tyr-Tic-Phe-NHsu